CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028913
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Small nuclear ribonucleoprotein 70 (U1) 
Protein Synonyms/Alias
 U1 small nuclear ribonucleoprotein polypeptide A, isoform CRA_a 
Gene Name
 Snrnp70 
Gene Synonyms/Alias
 Snrp70; mCG_23174 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
27PYLPPLEKLPHEKHHubiquitination[1]
118NYDTTESKLRREFEVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Ribonucleoprotein; Viral nucleoprotein; Virion. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 448 AA 
Protein Sequence
MTQFLPPNLL ALFAPRDPIP YLPPLEKLPH EKHHNQPYCG IAPYIREFED PRDAPPPTRA 60
ETREERMERK RREKIERRQQ EVETELKMWD PHNDPNAQGD AFKTLFVARV NYDTTESKLR 120
REFEVYGPIK RIHMVYSKRS GKPRGYAFIE YEHERDMHSA YKHADGKKID GRRVLVDVER 180
GRTVKGWRPR RLGGGLGGTR RGGADVNIRH SGRDDTSRYD ERPGPSPLPH RDRDRDRERE 240
RRERSRERDK ERERRRSRSR DRRRRSRSRD KDERRRSRER SKDKDRDRKR RSSRSRERAR 300
RERERKEELR GGGGGGGGGS GGGGGGDMAE PSEAGDGAPD DGPPGELGPE GPDGPEEKGR 360
DRDRERRRSH RSERERRRDR DRDRDREHKR GERGSERGRD EARGGGGSGQ DNGLEGLGSD 420
GRDMYMEAEG GDGYMAPENG YLMEAAPE 448 
Gene Ontology
 GO:0005634; C:nucleus; ISS:MGI.
 GO:0005681; C:spliceosomal complex; IEA:Compara.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:Compara.
 GO:0000398; P:mRNA splicing, via spliceosome; IEA:Compara.
 GO:0043484; P:regulation of RNA splicing; IEA:Compara. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom.
 IPR022023; U1snRNP70_N. 
Pfam
 PF00076; RRM_1
 PF12220; U1snRNP70_N 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS