| Tag | Content |
|---|
| CPLM ID | CPLM-023833 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 451 |
Protein Synonyms/Alias | Coactivator for steroid receptors |
Gene Name | ZNF451 |
Gene Synonyms/Alias | COASTER; KIAA0576; KIAA1702 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 106 | KNRAFREKIDFQHAH | ubiquitination | [1] | | 288 | SFKLGDNKGIAHPIS | ubiquitination | [1] | | 585 | LDNLTANKPSSAITV | ubiquitination | [1] | | 779 | IHQVHKEKSDEEEQQ | ubiquitination | [1] | | 790 | EEQQYVIKCGTCTKA | ubiquitination | [1] | | 827 | VAHFGSEKSNLYKFT | ubiquitination | [1] | | 832 | SEKSNLYKFTASASH | ubiquitination | [1] | | 845 | SHTERKLKQAINYSK | ubiquitination | [1] | | 852 | KQAINYSKSLDMEKG | ubiquitination | [1] | | 944 | LELENQFKKTQRPAH | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | May be involved in transcriptional regulation. Coactivator for steroid receptors. |
Sequence Annotation | ZN_FING 169 195 C2H2-type 1.
ZN_FING 253 277 C2H2-type 2.
ZN_FING 315 337 C2H2-type 3.
ZN_FING 362 386 C2H2-type 4.
ZN_FING 498 521 C2H2-type 5.
ZN_FING 531 554 C2H2-type 6.
ZN_FING 606 631 C2H2-type 7; atypical.
ZN_FING 636 659 C2H2-type 8.
ZN_FING 667 690 C2H2-type 9.
ZN_FING 753 776 C2H2-type 10.
ZN_FING 789 812 C2H2-type 11. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1061 AA |
Protein Sequence | MGDPGSEIIE SVPPAGPEAS ESTTDENEDD IQFVSEGPLR PVLEYIDLVS SDDEEPSTSY 60
TDENIKRKDH IDYQKDKVAL TLARLARHVE VEKQQKEEKN RAFREKIDFQ HAHGLQELEF 120
IRGHSDTEAA RLCVDQWLKM PGLKTGTINC GTKSSFRRGG HTWVSGKPIL CPIMHCNKEF 180
DNGHLLLGHL KRFDHSPCDP TITLHGPFFS SFACVVCYKK FVTQQQYRDH LFDKEATDDG 240
HNNNLLPQII QCFACPNCFL LFSRKEECSK HMSGKNHFHQ SFKLGDNKGI AHPISFPSFA 300
KKLLISLCKD VPFQVKCVAC HKTLRSHMEL TAHFRVHCRN AGPVAVAEKS ITQVAEKFIL 360
RGYCPDCNQV FVDETSTQNH KQNSGHKVRV INSVEESVLL YCHSSEGNKD PSSDLHLLLD 420
QSKFSSLKRT MSIKESSSLE CIAIPKKKMN LKDKSHEGVA CVQKEKSVVK TWFCECNQRF 480
PSEDAVEKHV FSANTMGYKC VVCGKVCDDS GVIRLHMSRI HGGAHLNNFL FWCRTCKKEL 540
TRKDTIMAHV TEFHNGHRYF YEMDEVEGET LPSSSTTLDN LTANKPSSAI TVIDHSPANS 600
SPRGKWQCRI CEDMFDSQEY VKQHCMSLAS HKFHRYSCAH CRKPFHKIET LYRHCQDEHD 660
NEIKIKYFCG LCDLIFNVEE AFLSHYEEHH SIDYVFVSEK TETSIKTEDD FPVIETSNQL 720
TCGCRESYIC KVNRKEDYSR CLQIMLDKGK LWFRCSLCSA TAQNLTDMNT HIHQVHKEKS 780
DEEEQQYVIK CGTCTKAFHD PESAQQHFHR KHCFLQKPSV AHFGSEKSNL YKFTASASHT 840
ERKLKQAINY SKSLDMEKGV ENDLSYQNIG GNTNWKPPLN CKIYNYLNRI GCFFLHPRCS 900
KRKDAADFAI CMHAGRLDEQ LPKQIPFTIL SGDQGFLELE NQFKKTQRPA HILNPHHLEG 960
DMMCALLNSI SDTTKECDSD DNMGAKNTSI GEEFISTEDV ELEEAIRRSL EEM 1013 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |