| Tag | Content |
|---|
| CPLM ID | CPLM-015823 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Lipid phosphate phosphatase-related protein type 4 |
Protein Synonyms/Alias | Brain-specific phosphatidic acid phosphatase-like protein 1; Plasticity-related gene 1 protein; PRG-1 |
Gene Name | Lppr4 |
Gene Synonyms/Alias | D3Bwg0562e; Kiaa0455; Prg1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 362 | PSRVLSAKNGSSGDG | ubiquitination | [1] | | 391 | ASSLTNLKRANADVE | ubiquitination | [1] | | 408 | TPRSPMGKESMVTFS | ubiquitination | [1] | | 460 | KSKNESRKMSLQVMD | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus (By similarity). |
Sequence Annotation | MOD_RES 218 218 Phosphoserine.
MOD_RES 347 347 Phosphoserine.
MOD_RES 417 417 Phosphothreonine.
CARBOHYD 215 215 N-linked (GlcNAc...) (Potential).
CARBOHYD 220 220 N-linked (GlcNAc...) (Potential).
CARBOHYD 269 269 N-linked (GlcNAc...) (Potential).
CARBOHYD 363 363 N-linked (GlcNAc...) (Potential).
CARBOHYD 433 433 N-linked (GlcNAc...) (Potential).
CARBOHYD 456 456 N-linked (GlcNAc...) (Potential).
CARBOHYD 515 515 N-linked (GlcNAc...) (Potential).
CARBOHYD 545 545 N-linked (GlcNAc...) (Potential).
CARBOHYD 570 570 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Hydrolase; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 766 AA |
Protein Sequence | MQRAGSSGAR GECDISGAGR LRLEQAARLG GRTVHTSPGG GLGARQAAGM SAKERPKGKV 60
IKDSVTLLPC FYFVELPILA SSVVSLYFLE LTDVFKPVHS GFSCYDRSLS MPYIEPTQEA 120
IPFLMLLSLA FAGPAITIMV GEGILYCCLS KRRNGAGLEP NINAGGCNFN SFLRRAVRFV 180
GVHVFGLCST ALITDIIQLS TGYQAPYFLT VCKPNYTSLN VSCKENSYIV EDICSGSDLT 240
VINSGRKSFP SQHATLAAFA AVYVSMYFNS TLTDSSKLLK PLLVFTFIIC GIICGLTRIT 300
QYKNHPVDVY CGFLIGGGIA LYLGLYAVGN FLPSEDSMLQ HRDALRSLTD LNQDPSRVLS 360
AKNGSSGDGI AHTEGILNRN HRDASSLTNL KRANADVEII TPRSPMGKES MVTFSNTLPR 420
ANTPSVEDPV RRNASIHASM DSARSKQLLT QWKSKNESRK MSLQVMDTEP EGQSPPRSIE 480
MRSSSEPSRV GVNGDHHVPG NQYLKIQPGT VPGCNNSMPG GPRVSIQSRP GSSQLVHIPE 540
ETQENISTSP KSSSARAKWL KAAEKTVACN RSNNQPRIMQ VIAMSKQQGV LQSSPKNAEG 600
STVTCTGSIR YKTLTDHEPS GIVRVEAHPE NNRPIIQIPS STEGEGSGSW KWKAPEKSSL 660
RQTYELNDLN RDSESCESLK DSFGSGDRKR SNIDSNEHHH HGITTIRVTP VEGSEIGSET 720
LSVSSSRDST LRRKGNIILI PERSNSPENT RNIFYKGTSP TRAYKD 766 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |