CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031789
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Diacylglycerol kinase, putative 
Protein Synonyms/Alias
  
Gene Name
 TGME49_039250, TGVEG_092360 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
371RLEGAHEKQREGKGDacetylation[1]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1841 AA 
Protein Sequence
MAQLASRSLC AGPSSACHGS RRFLLASLAV LFFVGLGCCL GVPVSPSPPA DASEDLFCTY 60
YGDSDCPSFL SFAAQTLGLC FRTWKNVSAA ALEAGLSGLA RLVPFLATDG ATSRMIHIVL 120
SVLATVCFLL LLSQIFWRYR VHHYNKSGSQ GLIPKSLHQW EPFSSSSSPR YCSVCRQLIS 180
GFLIYRNTGW ACTLCQRYAH TKCLRLAERL DCKTPCLPAP TPHVFIQGNL SAEATCCCCG 240
LACSSNFGLD GLRCLWCNRT LHEECRHRLP SPLCDLGPFR QLVLPPSAVS LSFSLLSSNR 300
GLLRVASSLW RRVGVKEVVK EGLREVQEGV RKFNEAIVQP LKKSLKFEQR HSEQVVQGER 360
GKTRLEGAHE KQREGKGDAH QLASEVEENR STEQASGEAE CRGNSGGSRE AESGEDPLAN 420
EATRESKSVE NESVDKEKEK DAQKKPREET CELVGEEEQE DATRGDGSDN PPVDPGGKKD 480
GGRSEPPRIL SRFSESKGQP KPTTTARDSS TDSAAPSLTA ASSDTQRLPE AEQTQDARSQ 540
RTDASPWGEN KSTGGGQAGE AVEQHGDSAA IARGTGDREA AETSQPHGWA PDSSGETLHT 600
PARDDPPCPH NARRKLASTQ RDEKQREGTA CLLASAASSF ACHGPPEPLG SHRPTAGAAT 660
SEEGDESRCQ KTESENDGLG SGDVVRVGGF TDFTEERSEE DLRTPSLEKG SEGQDARQTE 720
PDGRQKSGAP SEEALEKEDA SVVSGKKLRL KTPRRNGSSL PGAGSKTRRR ESSRTQMMYT 780
VAKAMPPMAA VWRLRSNPSL WFSEPQATPL LVFVNVKSGG QTGKAIYKDL VAILNPLQVI 840
DIQAEGGPSR ALSFFRPLAM TKRLRVLVCG GDGTVGWIID SIHKVYGAEA AEEERGSEAQ 900
TGDEVDSGEA AGKVGVEGEG RRGRRESEGV AWGSRDRACD LRSLVPVGIC PLGTGNDLSN 960
VLGWGFSFDG DIMKHLLKIQ SAVSSTLDLW KVKVISDKTN ATLVETTFSN YLDVGVAARI 1020
VLKFHKLREE NPELFQSRLG NKFLYGEVGF RDFLVTPNIA LRGLKIFCDG QEIALPYLEG 1080
ICVVNIPSFA GGVELWDTAP ESWAASASPG GLSPLPSLQY SSHDVGRAPQ QRQLLPSFPV 1140
SHNRESRSHA VSHLSQSAHA LPATRRRMHT RLSRAREDRQ AVEKVHLSDP PSFSPASSAA 1200
VFHLAPPRTS VSGRSVSASH HRSRRACEAA AEEFRACRCC CCGAQVTLPS FPRGDSVSTG 1260
ARSSSSRFSA CTDSAPPVSA SLRDFRLRER IAGTRTQSPH PRMSSSLSGE YCDALHTNFS 1320
RRKRARHERM HFSIHSLNSS SLPTSFVHAT SVRASSSALS SPPWEPAVEL RGASPTDAGS 1380
RRRCVSEESR EKRRLERTPV PDAGDRHEGD RGNLPSGSKA SRSTADPEIA PAVAPQELSP 1440
KDSDGCTRDR QKKSQSKAAE EDDDSVDRPF AGSSQRKSRV SCSTSPLKNR KTKDSHNRKR 1500
SARGAGRGVW QTRGQSLEDV SVSELSPRRA RRGRNVEERL RKGRVACSAW LRFPENRTKL 1560
CCGDCCGCSN ARDATYSPSI RPRRDEGEER EEGERTRFAS RREGEEREEG ERTRFASSRK 1620
SASCGPRGSE SEESNRGERE TVEASGREGR EMRRSQRAET LAVDRGPEEP KLEIACKPNV 1680
AGPQRLAGSE KNAESEEMKE QAQREEGTKS EIKSPNGPTR WRQQIINDQL IEVVGFKSLF 1740
HLGQVQVGLA KPVRLCQGRD IQLVLPQEIP LQIDGEPTML QAETTMHITW HGETPVLLAS 1800
DKSAQTQTLA AVQQVLATAY SRGLLSDYQF AQLANEFQKR F 1841 
Gene Ontology
 GO:0004143; F:diacylglycerol kinase activity; IEA:EC.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0004697; F:protein kinase C activity; IEA:EC.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR000756; Diacylglycerol_kin_accessory.
 IPR001206; Diacylglycerol_kinase_cat_dom.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd. 
Pfam
 PF00130; C1_1
 PF00609; DAGK_acc
 PF00781; DAGK_cat 
SMART
 SM00109; C1
 SM00045; DAGKa
 SM00046; DAGKc 
PROSITE
 PS50146; DAGK
 PS00479; ZF_DAG_PE_1
 PS50081; ZF_DAG_PE_2 
PRINTS