CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007357
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial outer membrane protein porin 2 
Protein Synonyms/Alias
 Voltage-dependent anion-selective channel protein 2; VDAC-2 
Gene Name
 POR2 
Gene Synonyms/Alias
 YIL114C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
111PQSIKNAKFNLSYAQacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Ion transport; Membrane; Mitochondrion; Mitochondrion outer membrane; Porin; Reference proteome; Transmembrane; Transmembrane beta strand; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 281 AA 
Protein Sequence
MALRFFNDIS RDVNGLFNRD FFHTNPLSLN ISTTTENGVN FTLKAKQGVT EGPIQTSVEG 60
RFYDRKEGVS LSQSWSNQNR LNTRIEFSKI APGWKGDVNA FLTPQSIKNA KFNLSYAQKS 120
FAARTSIDIL QPKDFVGSVT LGHRGFVGGT DIAYDTAAGL CARYAMSIGY LAREYSFILS 180
TNNRQCATAS FFQNVNRYLQ VGTKATLQSK TSSNMNIEFV TRYVPDSISQ VKAKIADSGL 240
TTLSYKRNLN KDISLGVGMS FNALQLTEPV HKFGWSLSFS P 281 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
 GO:0046930; C:pore complex; IEA:UniProtKB-KW.
 GO:0015288; F:porin activity; IEA:UniProtKB-KW.
 GO:0008308; F:voltage-gated anion channel activity; IGI:SGD.
 GO:0045454; P:cell redox homeostasis; IMP:SGD.
 GO:0051027; P:DNA transport; IMP:SGD. 
Interpro
 IPR023614; Porin_dom.
 IPR001925; Porin_Euk.
 IPR027246; Porin_Euk/Tom40. 
Pfam
 PF01459; Porin_3 
SMART
  
PROSITE
 PS00558; EUKARYOTIC_PORIN 
PRINTS
 PR00185; EUKARYTPORIN.