UniProt Accession

 RER1_HUMAN; O15258; O95322 

Genbank Protein ID

 AJ001421; AF091071; BC004965 

Genbank Nucleotide ID

 CAA04754.1; AAC72940.1; AAH04965.1 

Protein Name

 Protein RER1 

Protein Synonyms/Alias

  

Gene Name

 RER1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
14	VGESVHGKPSVVYRF	ubiquitination	[1, 2, 3]
35	IYQSWLDKSTPYTAV	ubiquitination	[4]
181	YIPFTHGKRRYRGKE	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine.
 MOD_RES 6 6 Phosphoserine.
 MOD_RES 95 95 Phosphoserine.  

Keyword

 Acetylation; Complete proteome; Golgi apparatus; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 196 AA 

Protein Sequence

Gene Ontology

 GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB.
 GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IDA:UniProtKB. 

Interpro

 IPR004932; Rer1. 

Pfam

 PF03248; Rer1 

SMART

  

PROSITE

  

PRINTS