CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037995
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger E-box-binding homeobox 1 
Protein Synonyms/Alias
  
Gene Name
 Zeb1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
387PKSCKSEKSPEDLTVacetylation[1]
395SPEDLTVKSEKDKSFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1008 AA 
Protein Sequence
MWYIYTMEYY SAIKNDFMKF VGKWLKLESI ILSELTQSQK DIHVKDDECD SDAENEQNHD 60
PNVEEFLQQQ DTAVIYPEAP EEDQRQGTPE ASGHDDNGTP DAFSQLLTCP YCDRGYKRFT 120
SLKEHIKYRH EKNEDNFSCS LCSYTFAYRT QLERHMTSHK SGREQRHVTQ SGGNRKFKCT 180
ECGKAFKYKH HLKEHLRIHS GSPTRPQIRQ KIENKPLQEP LSVNQIKTEP VDYEFKPIVV 240
ASGINCSTPL QNGVFSGGGQ LQATSSPQGV VQAVVLPTVG LVSPISINLS DIQNVLKVAV 300
DGNIIRQVLE NNQASLASKE QEAVSASSIQ QGGHSVISAI SLPLVDQDGT TKIIINYSLE 360
QPGQLQVVPQ NLKKENPAPP KSCKSEKSPE DLTVKSEKDK SFDGAADEST CLLCEDCPGD 420
LNALPELKHY DPEHPAQPPP PAPATEKPES SASSAGNGDL SPSQPPLKNL LSLLKAYYAL 480
NAQPSTEELT KIADSVNLPL DVVKKWFEKM QAGQIPGQSL EPPSPGPGSG NIPKTEEQPQ 540
PVDGNEPQED STRGQSPLKM TSSPVLPVGS AINGSRSCTS SPSPLNLSSA RNPQGYSCVS 600
EGTQEEPQVE PLDLSLPKQQ GELLERSTVS SVYQNSVYSV QEEPLNLSCA KKEPQKDSCV 660
TDSEPVVNVV PPSANPINIA IPTVTAQLPT IVAIADQNSV PCLRALAANK QTILIPQVAY 720
TYSATVSPAM QEPPVKVIQP NGNQDERQDT SSEGVSVEDQ NDSDCTPPKK KTRKAENGMY 780
ACDLCDKIFQ KSSSLLRHKY EHTGKRPHEC GICRKAFKHK HHLIEHMRLH SGEKPYQCDK 840
CGKRFSHSGS YSQHMNHRYS YCKRGAEDRD AMEQEDTGPE ALPEVLPTEL VGARASPSQA 900
DSDERESLTR EEDEDSEKEE EEEDKEMEEL QEDKECENPQ EEEEEEEEEE EEEEEEEEEE 960
AEEAEHEAAA AKTGGAVEEE AAQQAGSFQQ KASGSESKRL SEEKTNEA 1008 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR013544; DUF1725.
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF08333; DUF1725
 PF00046; Homeobox
 PF00096; zf-C2H2 
SMART
 SM00389; HOX
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS