UniProt Accession

 B0V2V6_MOUSE; B0V2V6 

Genbank Protein ID

 CT033751; CT033755 

Genbank Nucleotide ID

  

Protein Name

 Bromodomain-containing protein 4 

Protein Synonyms/Alias

  

Gene Name

 Brd4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
99	LNLPDYYKIIKTPMD	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Bromodomain; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 557 AA 

Protein Sequence

Gene Ontology

 GO:0000794; C:condensed nuclear chromosome; IDA:MGI.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0000790; C:nuclear chromatin; IDA:MGI.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0007059; P:chromosome segregation; IMP:MGI.
 GO:0044154; P:histone H3-K14 acetylation; IMP:MGI.
 GO:0043983; P:histone H4-K12 acetylation; IMP:MGI.
 GO:0001833; P:inner cell mass cell proliferation; IMP:MGI.
 GO:0043388; P:positive regulation of DNA binding; IDA:MGI.
 GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Compara.
 GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:Compara.
 GO:0006468; P:protein phosphorylation; IPI:MGI.
 GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; IEA:Compara. 

Interpro

 IPR001487; Bromodomain.
 IPR018359; Bromodomain_CS. 

Pfam

 PF00439; Bromodomain 

SMART

 SM00297; BROMO 

PROSITE

 PS00633; BROMODOMAIN_1
 PS50014; BROMODOMAIN_2 

PRINTS

 PR00503; BROMODOMAIN.