CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014849
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pre-mRNA-splicing factor ISY1 homolog 
Protein Synonyms/Alias
  
Gene Name
 Isy1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
24QAQLEEGKVKERRPFacetylation[1]
101LGGPDYGKVGPKMLDacetylation[1]
121VPGNRGYKYFGAAKDacetylation[1]
127YKYFGAAKDLPGVREacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May play a role in pre-mRNA splicing (Potential). 
Sequence Annotation
 MOD_RES 127 127 N6-acetyllysine (By similarity).
 MOD_RES 246 246 Phosphoserine (By similarity).  
Keyword
 Acetylation; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Spliceosome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 284 AA 
Protein Sequence
MARNAEKAMT ALARFRQAQL EEGKVKERRP FLASECTELP KAEKWRRQII GEISKKVAQI 60
QNAGLGEFRI RDLNDEINKL LREKGHWEVR IKELGGPDYG KVGPKMLDHE GKEVPGNRGY 120
KYFGAAKDLP GVRELFEKEP LPPPRKTRAE LMKAIDFEYY GYLDEDDGVI VPLEQEYEKR 180
LRAELVEKWK AEREARLARG EKEEEEEEEE INIYAVTEEE SDEEGSQEKA GEDGQQKFIA 240
HVPVPSQQEI EEALVRRKKM ELLQKYASET LQAQSEEAKR LLGY 284 
Gene Ontology
 GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. 
Interpro
 IPR009360; Isy1. 
Pfam
 PF06246; Isy1 
SMART
  
PROSITE
  
PRINTS