UniProt Accession

 D3YU15_MOUSE; D3YU15 

Genbank Protein ID

 AC123684; AC126412; CH466532 

Genbank Nucleotide ID

 EDL11993.1 

Protein Name

 Dimethylarginine dimethylaminohydrolase 1, isoform CRA_a 

Protein Synonyms/Alias

 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 

Gene Name

 Ddah1 

Gene Synonyms/Alias

 mCG_7778 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
56	EILADTFKDYAVSTV	acetylation	[1]
56	EILADTFKDYAVSTV	ubiquitination	[2]
108	MSDHRYDKLTVPDDM	acetylation	[1]
144	EEYPESAKVYEKLKD	acetylation	[1]
144	EEYPESAKVYEKLKD	ubiquitination	[2]
150	AKVYEKLKDHLLIPV	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Hydrolase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 182 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0016597; F:amino acid binding; IEA:Compara.
 GO:0016403; F:dimethylargininase activity; ISA:MGI.
 GO:0008270; F:zinc ion binding; ISA:MGI.
 GO:0006525; P:arginine metabolic process; IEA:Compara.
 GO:0000052; P:citrulline metabolic process; IEA:Compara.
 GO:0006809; P:nitric oxide biosynthetic process; ISA:MGI.
 GO:0045766; P:positive regulation of angiogenesis; IEA:Compara.
 GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Compara.
 GO:0017014; P:protein nitrosylation; ISA:MGI. 

Interpro

 IPR003198; Amidino_trans. 

Pfam

 PF02274; Amidinotransf 

SMART

  

PROSITE

  

PRINTS