CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045228
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 NAD-dependent protein deacetylase sirtuin-6 
Protein Synonyms/Alias
  
Gene Name
 SIRT6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
15GLSPYADKGKCGLPEubiquitination[1]
17SPYADKGKCGLPEIFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 187 AA 
Protein Sequence
MSVNYAAGLS PYADKGKCGL PEIFDPPEEL ERKVWELARL VWQSSSVVFH TGAGISTASG 60
IPDFRDKLAE LHGNMFVEEC AKCKTQYVRD TVVGTMGLKA TGRLCTVAKA RGLRACRGEL 120
RDTILDWEDS LPDRDLALAD EASRSGPAGT CRWLPSAGEA AWSSSTCSPP STTAMLTSAS 180
MATLTRS 187 
Gene Ontology
 GO:0070403; F:NAD+ binding; IEA:InterPro. 
Interpro
 IPR003000; Sirtuin.
 IPR026590; Ssirtuin_cat_dom. 
Pfam
  
SMART
  
PROSITE
 PS50305; SIRTUIN 
PRINTS