CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041917
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 KDEL (Lys-Asp-Glu-Leu) containing 2, isoform CRA_b 
Protein Synonyms/Alias
 Protein Kdelc2 
Gene Name
 Kdelc2 
Gene Synonyms/Alias
 mCG_5638 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
72TQFKVVVKSLSPKELacetylation[1]
438EEAKKIAKEGQLTARacetylation[2]
438EEAKKIAKEGQLTARsuccinylation[2]
463YYYRVLQKYAERQASacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 503 AA 
Protein Sequence
MQALPLGLQL ALLVAAGAGA RVSAPRSLAW GPGLQAAAVL PVRYFFLQSV DSDGRNFTSS 60
PPGQTQFKVV VKSLSPKELV RIYVPKPLDR NDGTFLVRYR MHETAHKGLK IEILHGSEHV 120
AHSPYILKGP VYHEYCDCPE DDPQVWQETL SCPASEPQIE QDFVSFPSIN LQQMLKEVPT 180
RFGDERGAVV HYTILNNHIY RRSLGKYTDF KMFSDEILLS LARKVTLPDL EFYINLGDWP 240
LEHRKVNDTP GPIPIISWCG SLDSRDIILP TYDVTHSTLE AMRGVTNDLL SVQGNTGPSW 300
INKTEKAFFR GRDSREERLQ LVLLSKENPQ LLDAGITGYF FFQEKEKELG KAKLMGFFDF 360
FKYKYQVNVD GTVAAYRYPY LMLGDSLVLK QESPYYEHFY VALKPWKHYV PIKRNLGDLL 420
EKVKWAKEND EEAKKIAKEG QLTARDLLQP PRLYCYYYRV LQKYAERQAS KPMIRDGMEL 480
VPQPDDGTSI CQCHRRRPER EEL 503 
Gene Ontology
  
Interpro
 IPR001298; Filamin.
 IPR017868; Filamin/ABP280_repeat-like.
 IPR014756; Ig_E-set.
 IPR006598; LipoPS_modifying. 
Pfam
 PF00630; Filamin
 PF05686; Glyco_transf_90 
SMART
 SM00672; CAP10
 SM00557; IG_FLMN 
PROSITE
 PS50194; FILAMIN_REPEAT 
PRINTS