UniProt Accession

 D3Z2Q0_MOUSE; D3Z2Q0 

Genbank Protein ID

 AC122902; AC140786 

Genbank Nucleotide ID

  

Protein Name

 Putative adenosylhomocysteinase 2 

Protein Synonyms/Alias

  

Gene Name

 Ahcyl1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
53	EKQQTNSKGSSNFCV	ubiquitination	[1]
61	GSSNFCVKNIKQAEF	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 210 AA 

Protein Sequence

Gene Ontology

 GO:0004013; F:adenosylhomocysteinase activity; IEA:InterPro.
 GO:0006378; P:mRNA polyadenylation; IDA:MGI.
 GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
 GO:0010765; P:positive regulation of sodium ion transport; IGI:MGI.
 GO:0006611; P:protein export from nucleus; IDA:MGI.
 GO:0044070; P:regulation of anion transport; IGI:MGI.
 GO:0032412; P:regulation of ion transmembrane transporter activity; IGI:MGI.
 GO:0031440; P:regulation of mRNA 3'-end processing; IDA:MGI. 

Interpro

 IPR000043; Adenosylhomocysteinase.
 IPR020082; S-Ado-L-homoCys_hydrolase_CS. 

Pfam

 PF05221; AdoHcyase 

SMART

  

PROSITE

 PS00738; ADOHCYASE_1 

PRINTS