CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cyclin A2, isoform CRA_b 
Protein Synonyms/Alias
 Protein Ccna2 
Gene Name
 Ccna2 
Gene Synonyms/Alias
 rCG_41610 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
62TRRVAPLKDLPINDEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Cell cycle; Cell division; Complete proteome; Cyclin; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 418 AA 
Protein Sequence
MPGNSRQAGS ALLSQQEDQE NVNPEKVAPA QQPRAQAVLK AGKVRGPAPQ QRLKTRRVAP 60
LKDLPINDEH VPTVPSWKAV SKQPAFTIHV DEAEETQKRP AEQKETQCED ALAFSAAVSL 120
PGARKPLVPL DYPMDGSFES PHAMDISIVL EDEKPVNVNE VPDYHEDIHT YLREMEVKCK 180
PKVSYMKRQP DITNSMRAIL VDWLVEVGEE YKLQNETLHL AVNYIDRFLS SMSVLRGKLQ 240
LVGTAAMLLA SKFEEIYPPE VAEFVYITDD TYSKKQVLRM EHLVLKVLAF DLAAPTVNQF 300
LTQYFLHLQP ANCKVESLAM FLGELSLIDA DPYLKYLPSL IAGAAFHLAL YTVTGQSWPE 360
SLVQKTGYTL ESLKPCLMDL HQTYLKAPQH AQQSIREKYK HSKYHSVSLL NPPETLNV 418 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0001939; C:female pronucleus; IEA:Compara.
 GO:0001940; C:male pronucleus; IEA:Compara.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0031100; P:organ regeneration; IEP:RGD.
 GO:0048146; P:positive regulation of fibroblast proliferation; IMP:RGD.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0007265; P:Ras protein signal transduction; IEA:Compara.
 GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
 GO:0032355; P:response to estradiol stimulus; IEP:RGD.
 GO:0033762; P:response to glucagon stimulus; IEP:RGD. 
Interpro
 IPR013763; Cyclin-like.
 IPR014400; Cyclin_A/B/D/E.
 IPR004367; Cyclin_C-dom.
 IPR006671; Cyclin_N. 
Pfam
 PF02984; Cyclin_C
 PF00134; Cyclin_N 
SMART
 SM00385; CYCLIN 
PROSITE
 PS00292; CYCLINS 
PRINTS