CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040769
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transducin-like enhancer protein 4 
Protein Synonyms/Alias
 cDNA FLJ58005 
Gene Name
 TLE4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
212KKQKTEEKEIAARYDacetylation[1]
256PRENGLDKTRLLKKDacetylation[1]
283STPSSKSKELSLNEKacetylation[1]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 748 AA 
Protein Sequence
MIRDLSKMYP QTRHPAPHQP AQPFKFTISE SCDRIKEEFQ FLQAQYHSLK LECEKLASEK 60
TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVIP FLSQEQQLQA QHLSHGHGLP 120
VPLTPHPSGL QPPAIPPIGS SAGLLALSSA LGGQSHLPIK DEKKHHDNDH QRDRDSIKSS 180
SVSPSASFRG AEKHRNSADY SSESKKQKTE EKEIAARYDS DGEKSDDNLV VDVSNEDPSS 240
PRGSPAHSPR ENGLDKTRLL KKDAPISPAS IASSSSTPSS KSKELSLNEK STTPVSKSNT 300
PTPRTDAPTP GSNSTPGLRP VPGKPPGVDP LASSLRTPMA VPCPYPTPFG IVPHAGMNGE 360
LTSPGAAYAG LHNISPQMSA AAAAAAAAAA YGRSPVVGFD PHHHMRVPAI PPNLTGIPGG 420
KPAYSFHVSA DGQMQPVPFP PDALIGPGIP RHARQINTLN HGEVVCAVTI SNPTRHVYTG 480
GKGCVKVWDI SHPGNKSPVS QLDCLNRDNY IRSCRLLPDG RTLIVGGEAS TLSIWDLAAP 540
TPRIKAELTS SAPACYALAI SPDSKVCFSC CSDGNIAVWD LHNQTLVRQF QGHTDGASCI 600
DISNDGTKLW TGGLDNTVRS WDLREGRQLQ QHDFTSQIFS LGYCPTGEWL AVGMENSNVE 660
VLHVTKPDKY QLHLHESCVL SLKFAHCGKW FVSTGKDNLL NAWRTPYGAS IFQSKESSSV 720
LSCDISVDDK YIVTGSGDKK ATVYEVIY 748 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR005617; Groucho/TLE_N.
 IPR009146; Groucho_enhance.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF03920; TLE_N
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR01850; GROUCHOFAMLY.