CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042171
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 6-phosphofructokinase 
Protein Synonyms/Alias
 Phosphohexokinase 
Gene Name
 LOC100733625 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
443KRFDEAMKLRGRSFMacetylation[1]
749FDRNFATKMGAKAMNacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Glycolysis; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 851 AA 
Protein Sequence
MHKEEFHLKF FMCVIQSRRL VRTPQRTAGE TSNSSMLIPK LRPRTDTLKS LDTVDDPATM 60
EGIPIFKTEW IMTHEEHHAA KTLGIGKAIA VLTSGGDAQG MNAAVRAVVR VGIFTGARVF 120
FVHEGYQGLV DGGDNIREAT WESVSMMLQL GGTVIGSARC KDFREREGRL RAAHNLVKRG 180
ITNLCVIGGD GSLTGADTFR SEWSDLLNDL QKAGKITAEE AKKSSFLNIV GLVGSIDNDF 240
CGTDMTIGTD SALHRIIEIV DAITTTAQSH QRTFVLEVMG RHCGYLALVT SLSCGADWVF 300
IPECPPDDDW EEHLCRRLSE TRTRGSRLNI IIVAEGAIDK NGKPITSEDI KNLVVTRLGY 360
DTRVTVLGHV QRGGTPSAFD RILGSRMGVE AVMALLEGTP DTPACVVSLS GNQAVRLPLM 420
ECVQVTKDVT KAMDDKRFDE AMKLRGRSFM NNWEVYKLLA HVRPPVSKSG SFTVAVMNVG 480
APAAGMNAAV RSTVRIGLIQ GNRVLVVHDG FEGLAKGQIE EAGWSYVGGW TGQGGSKLGT 540
KRTLPKKSFE QISANITKFN IQGLVIIGGF EAYTGGLELM EGRKQFDELC IPFVVIPATV 600
SNNVPGSDFS VGADTALNTI CTTCDRIKQS AAGTKRRVFI IETMGGYCGY LATMAGLAAG 660
ADAAYIFEEP FTIRDLQANV EHLVQKMKTT VKRGLVLRNE KCNDNYTTDF IFNLYSEEGK 720
GIFDSRKNVL GHMQQGGSPT PFDRNFATKM GAKAMNWMSG KIKESYRNGR IFANTPDSGC 780
VLGMRKRALV FQPVTELKEQ TDFEHRIPKE QWWLKLRPIL KILAKYEIDL DTSEHAHLEH 840
ISRKRSGEAT V 851 
Gene Ontology
 GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
 GO:0016324; C:apical plasma membrane; IEA:Compara.
 GO:0003872; F:6-phosphofructokinase activity; IEA:EC.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0070061; F:fructose binding; IEA:Compara.
 GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
 GO:0042593; P:glucose homeostasis; IEA:Compara.
 GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway.
 GO:0046716; P:muscle cell homeostasis; IEA:Compara.
 GO:0032024; P:positive regulation of insulin secretion; IEA:Compara.
 GO:0051259; P:protein oligomerization; IEA:Compara. 
Interpro
 IPR009161; 6-phosphofructokinase_euk.
 IPR022953; Phosphofructokinase.
 IPR015912; Phosphofructokinase_CS.
 IPR000023; Phosphofructokinase_dom. 
Pfam
 PF00365; PFK 
SMART
  
PROSITE
 PS00433; PHOSPHOFRUCTOKINASE 
PRINTS
 PR00476; PHFRCTKINASE.