UniProt Accession

 SOD1A_XENLA; P13926; Q0P3T2; Q2VPM0 

Genbank Protein ID

 X16585; BC108610; BC122466 

Genbank Nucleotide ID

 CAA34602.1; AAI08611.1; AAI22467.1 

Protein Name

 Superoxide dismutase [Cu-Zn] A 

Protein Synonyms/Alias

 XSODA 

Gene Name

 sod1-a 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Xenopus laevis (African clawed frog) 

NCBI Taxa ID

 8355 

Lysine Modification

Position	Peptide	Type	References
126	EKQDDLGKGGDDESL	acetylation	[1]

Reference

 [1] A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2.
 Andersen JL, Thompson JW, Lindblom KR, Johnson ES, Yang CS, Lilley LR, Freel CD, Moseley MA, Kornbluth S.
 Mol Cell. 2011 Sep 2;43(5):834-42. [PMID: 21884983] 

Functional Description

 Destroys radicals which are normally produced within the cells and which are toxic to biological systems. 

Sequence Annotation

 METAL 45 45 Copper; catalytic (By similarity).
 METAL 47 47 Copper; catalytic (By similarity).
 METAL 62 62 Copper; catalytic (By similarity).
 METAL 62 62 Zinc; structural (By similarity).
 METAL 70 70 Zinc; structural (By similarity).
 METAL 79 79 Zinc; structural (By similarity).
 METAL 82 82 Zinc; structural (By similarity).
 METAL 118 118 Copper; catalytic (By similarity).
 DISULFID 56 144 By similarity.  

Keyword

 Antioxidant; Copper; Cytoplasm; Direct protein sequencing; Disulfide bond; Metal-binding; Oxidoreductase; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 151 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004784; F:superoxide dismutase activity; IEA:EC.
 GO:0006801; P:superoxide metabolic process; IEA:InterPro. 

Interpro

 IPR024134; SOD_Cu/Zn_/chaperones.
 IPR018152; SOD_Cu/Zn_BS.
 IPR001424; SOD_Cu_Zn_dom. 

Pfam

 PF00080; Sod_Cu 

SMART

  

PROSITE

 PS00087; SOD_CU_ZN_1
 PS00332; SOD_CU_ZN_2 

PRINTS

 PR00068; CUZNDISMTASE.