UniProt Accession

 RS6_ECOLI; P02358; Q2M6A5 

Genbank Protein ID

 X04022; U14003; U00096; AP009048 

Genbank Nucleotide ID

 CAA27652.1; AAA97096.1; AAC77157.5; BAE78201.1 

Protein Name

 30S ribosomal protein S6 

Protein Synonyms/Alias

 30S ribosomal protein S6, fully modified isoform; 30S ribosomal protein S6, non-modified isoform 

Gene Name

 rpsF 

Gene Synonyms/Alias

 b4200; JW4158 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
35	AITGAEGKIHRLEDW	acetylation	[1]
35	AITGAEGKIHRLEDW	pupylation	[2]
53	QLAYPINKLHKAHYV	acetylation	[1]
56	YPINKLHKAHYVLMN	acetylation	[1, 3, 4]
93	RSMVMRTKHAVTEAS	acetylation	[1, 4, 5]
104	TEASPMVKAKDERRE	acetylation	[1]
106	ASPMVKAKDERRERR	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Reconstitution of the Mycobacterium tuberculosis pupylation pathway in Escherichia coli.
 Cerda-Maira FA, McAllister F, Bode NJ, Burns KE, Gygi SP, Darwin KH.
 EMBO Rep. 2011 Jul 8;12(8):863-70. [PMID: 21738222]
 [3] The diversity of lysine-acetylated proteins in Escherichia coli.
 Yu BJ, Kim JA, Moon JH, Ryu SE, Pan JG.
 J Microbiol Biotechnol. 2008 Sep;18(9):1529-36. [PMID: 18852508]
 [4] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [5] Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli.
 Zhang J, Sprung R, Pei J, Tan X, Kim S, Zhu H, Liu CF, Grishin NV, Zhao Y.
 Mol Cell Proteomics. 2009 Feb;8(2):215-25. [PMID: 18723842] 

Functional Description

 Binds together with S18 to 16S ribosomal RNA. 

Sequence Annotation

 MOD_RES 93 93 N6-acetyllysine.  

Keyword

 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 135 AA 

Protein Sequence

Gene Ontology

 GO:0022627; C:cytosolic small ribosomal subunit; IDA:EcoliWiki.
 GO:0019843; F:rRNA binding; IEA:HAMAP.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:HAMAP. 

Interpro

 IPR000529; Ribosomal_S6.
 IPR020815; Ribosomal_S6_CS.
 IPR020814; Ribosomal_S6_plastid/chlpt.
 IPR014717; Transl_elong_EF1B/ribosomal_S6. 

Pfam

 PF01250; Ribosomal_S6 

SMART

  

PROSITE

 PS01048; RIBOSOMAL_S6 

PRINTS