CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041790
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Myosin, heavy polypeptide 10, non-muscle, isoform CRA_b 
Protein Synonyms/Alias
 Myosin-10 
Gene Name
 Myh10 
Gene Synonyms/Alias
 rCG_34638 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
362QFGNISFKKERNTDQacetylation[1]
442WLVHRINKALDRTKRacetylation[1]
552TDKTFVEKLVQEQGSacetylation[1]
562QEQGSHSKFQKPRQLacetylation[1]
620RFVAELWKDVDRIVGacetylation[1]
663LYKESLTKLMATLRNacetylation[1]
840QWWRVFTKVKPLLQVacetylation[1]
917RARLAAKKQELEEILacetylation[1]
1021QLAEEEEKAKNLAKIacetylation[1]
1031NLAKIRNKQEVMISDacetylation[1]
1055KTRQELEKAKRKLDGacetylation[1]
1087ELKVQLTKKEEELQGacetylation[1]
1131QEDFESEKASRNKAEacetylation[1]
1219LEQAKRFKANLEKNKacetylation[1]
1301TLLEEAEKKGMKFAKacetylation[1]
1364EARKNLEKQVLALQSacetylation[1]
1394IEGLEEAKKKLLKDVacetylation[1]
1399EAKKKLLKDVEALSQacetylation[1]
1411LSQRLEEKVLAYDKLacetylation[1]
1417EKVLAYDKLEKTKNRacetylation[1]
1596EKKRLLLKQVRELEAacetylation[1]
1645KARDEVIKQLRKLQAacetylation[1]
1655RKLQAQMKDYQRELEacetylation[1]
1731KSALLDEKRRLEARIacetylation[1]
1800QNKELKAKLQELEGAacetylation[1]
1842KERAAANKLVRRTEKacetylation[1]
1869RRHADQYKEQMEKANacetylation[1]
1874QYKEQMEKANARMKQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; ATP-binding; Coiled coil; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1976 AA 
Protein Sequence
MAQRTGLEDP ERYLFVDRAV IYNPATQADW TAKKLVWIPS ERHGFEAASI KEERGDEVMV 60
ELAENGKKAM VNKDDIQKMN PPKFSKVEDM AELTCLNEAS VLHNLKDRYY SGLIYTYSGL 120
FCVVINPYKN LPIYSENIIE MYRGKKRHEM PPHIYAISES AYRCMLQDRE DQSILCTGES 180
GAGKTENTKK VIQYLAHVAS SHKGRKDHNI PGELERQLLQ ANPILESFGN AKTVKNDNSS 240
RFGKFIRINF DVTGYIVGAN IETYLLEKSR AVRQAKDERT FHIFYQLLSG AGEHLKSDLL 300
LEGFNNYRFL SNGYIPIPGQ QDKDNFQETM EAMHIMGFSH EEILSMLKVV SSVLQFGNIS 360
FKKERNTDQA SMPENTVAQK LCHLLGMNVM EFTRAILTPR IKVGRDYVQK AQTKEQADFA 420
VEALAKATYE RLFRWLVHRI NKALDRTKRQ GASFIGILDI AGFEIFELNS FEQLCINYTN 480
EKLQQLFNHT MFILEQEEYQ REGIEWNFID FGLDLQPCID LIERPANPPG VLALLDEECW 540
FPKATDKTFV EKLVQEQGSH SKFQKPRQLK DKADFCIIHY AGKVDYKADE WLMKNMDPLN 600
DNVATLLHQS SDRFVAELWK DVDRIVGLDQ VTGMTETAFG SAYKTKKGMF RTVGQLYKES 660
LTKLMATLRN TNPNFVRCII PNHEKRAGKL DPHLVLDQLR CNGVLEGIRI CRQGFPNRIV 720
FQEFRQRYEI LTPNAIPKGF MDGKQACERM IRALELDPNL YRIGQSKIFF RAGVLAHLEE 780
ERDLKITDII IFFQAVCRGY LARKAFAKKQ QQLSALKVLQ RNCAAYLKLR HWQWWRVFTK 840
VKPLLQVTRQ EEELQAKDEE LLKVKEKQTK VEGELEEMER KHQQLLEEKN ILAEQLQAET 900
ELFAEAEEMR ARLAAKKQEL EEILHDLESR VEEEEERNQI LQNEKKKMQA HIQDLEEQLD 960
EEEGARQKLQ LEKVTAEAKI KKMEEEVLLL EDQNSKFIKE KKLMEDRIAE CSSQLAEEEE 1020
KAKNLAKIRN KQEVMISDLE ERLKKEEKTR QELEKAKRKL DGETTDLQDQ IAELQAQVDE 1080
LKVQLTKKEE ELQGALARGD DETLHKNNAL KVARELQAQI AELQEDFESE KASRNKAEKQ 1140
KRDLSEELEA LKTELEDTLD TTAAQQELRT KREQEVAELK KALEDETKNH EAQIQDMRQR 1200
HATALEELSE QLEQAKRFKA NLEKNKQGLE TDNKELACEV KVLQQVKAES EHKRKKLDAQ 1260
VQELHAKVSE GDRLRVELAE KANKLQNELD NVSTLLEEAE KKGMKFAKDA AGLESQLQDT 1320
QELLQEETRQ KLNLSSRIRQ LEEEKNSLQE QQEEEEEARK NLEKQVLALQ SQLADTKKKV 1380
DDDLGTIEGL EEAKKKLLKD VEALSQRLEE KVLAYDKLEK TKNRLQQELD DLTVDLDHQR 1440
QIVSNLEKKQ KKFDQLLAEE KGISARYAEE RDRAEAEARE KETKALSLAR ALEEALEAKE 1500
EFERQNKQLR ADMEDLMSSK DDVGKNVHEL EKSKRALEQQ VEEMRTQLEE LEDELQATED 1560
AKLRLEVNMQ AMKAQFERDL QTRDEQNEEK KRLLLKQVRE LEAELEDERK QRALAVASKK 1620
KMEIDLKDLE AQIEAANKAR DEVIKQLRKL QAQMKDYQRE LEEARASRDE IFAQSKESEK 1680
KLKSLEAEIL QLQEELASSE RARRHAEQER DELADEIANS ASGKSALLDE KRRLEARIAQ 1740
LEEELEEEQS NMELLNDRFR KTTLQVDTLN TELAAERSAA QKSDNARQQL ERQNKELKAK 1800
LQELEGAVKS KFKATISALE AKIGQLEEQL EQEAKERAAA NKLVRRTEKK LKEIFMQVED 1860
ERRHADQYKE QMEKANARMK QLKRQLEEAE EEATRANASR RKLQRELDDA TEANEGLSRE 1920
VSTLKNRLRR GGPISFSSSR SGRRQLHIEG ASLELSDDDT ESKTSDVNET QPPQSE 1976 
Gene Ontology
 GO:0030424; C:axon; IEA:Compara.
 GO:0005938; C:cell cortex; IEA:Compara.
 GO:0043197; C:dendritic spine; IEA:Compara.
 GO:0030426; C:growth cone; IEA:Compara.
 GO:0016460; C:myosin II complex; IEA:Compara.
 GO:0031594; C:neuromuscular junction; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005819; C:spindle; IEA:Compara.
 GO:0001725; C:stress fiber; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro.
 GO:0007512; P:adult heart development; IEA:Compara.
 GO:0007411; P:axon guidance; IEA:Compara.
 GO:0055003; P:cardiac myofibril assembly; IEA:Compara.
 GO:0008283; P:cell proliferation; IEA:Compara.
 GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Compara.
 GO:0006887; P:exocytosis; IEA:Compara.
 GO:0021592; P:fourth ventricle development; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0021670; P:lateral ventricle development; IEA:Compara.
 GO:0000281; P:mitotic cytokinesis; IEA:Compara.
 GO:0050885; P:neuromuscular process controlling balance; IEA:Compara.
 GO:0001764; P:neuron migration; IEA:Compara.
 GO:0007097; P:nuclear migration; IEA:Compara.
 GO:0001778; P:plasma membrane repair; IEA:Compara.
 GO:0008360; P:regulation of cell shape; IEA:Compara.
 GO:0060041; P:retina development in camera-type eye; IEA:Compara.
 GO:0006930; P:substrate-dependent cell migration, cell extension; IEA:Compara.
 GO:0021678; P:third ventricle development; IEA:Compara.
 GO:0055015; P:ventricular cardiac muscle cell development; IEA:Compara. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR027401; Myosin-like_IQ_dom.
 IPR001609; Myosin_head_motor_dom.
 IPR004009; Myosin_N.
 IPR008989; Myosin_S1_N.
 IPR002928; Myosin_tail.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00612; IQ
 PF00063; Myosin_head
 PF02736; Myosin_N
 PF01576; Myosin_tail_1 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.