| Tag | Content |
|---|
| CPLM ID | CPLM-008671 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | N-acetyltransferase SLI1 |
Protein Synonyms/Alias | Sphingosine-like immunosuppressant resistant protein 1 |
Gene Name | SLI1 |
Gene Synonyms/Alias | YGR212W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 229 | PKDLLDDKPSDGTQK | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Confers resistance to the sphingolipid biosynthesis inhibitor drug myriocin (ISP-1). Inactivates ISP-1 by converting it into N-acetyl-myriocin. Cooperates with YPK1 in mediating resistance to myriocin. |
Sequence Annotation | |
Keyword | Acyltransferase; Complete proteome; Endoplasmic reticulum; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 468 AA |
Protein Sequence | MNLKLSAIES YFFHRSRLNL HSCFYVGIKL NELPKKSQLI AALKYTVIQH ERLTCNVFYD 60
ELKKENFLQN ILEPLKFCDL VEYRHDWDQL GETEINHIFQ RYNFSYNENK PLWKILILPN 120
QNQMLLLTDH VLMDGMSAIH VWETFMEGLQ MQQPVEIDET IYSPSLNSST EKIMSAPLYG 180
DWPIPWNWHI VRQLVSRLHY WFPQTVVKNN RNLIQFANYS FPKDLLDDKP SDGTQKYKVK 240
NTNHQWEFRL SPTHLNDILQ ECKANNTSLT SLLGALVCTS FEKIAAHEYT GSFLKIELPM 300
NIRKPFERVL KLPSDDKLAV GNFIAVIEFN HKLHQNRGIW DIASQIQRAI RSSSEDKIID 360
KVNEVKLLEV ISSQQYIEDK ISLNNGPSST FEVTNLGFQT FKDACNTSLP FYIVDATFNE 420
PQGISSIFSL SVISTPGNGL HCCISYPNTL TKVLEPHWQY MKDYLNLY 468 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. GO:0004026; F:alcohol O-acetyltransferase activity; IEA:InterPro. GO:0008080; F:N-acetyltransferase activity; IMP:SGD. GO:0006066; P:alcohol metabolic process; IEA:InterPro. GO:0042493; P:response to drug; IDA:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |