| Tag | Content |
|---|
| CPLM ID | CPLM-007293 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | T-complex protein 1 subunit zeta |
Protein Synonyms/Alias | TCP-1-zeta; Acute morphine dependence-related protein 2; CCT-zeta-1; HTR3; Tcp20 |
Gene Name | CCT6A |
Gene Synonyms/Alias | CCT6; CCTZ |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 58 | AGDIKLTKDGNVLLH | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. |
Sequence Annotation | MOD_RES 199 199 N6-acetyllysine.
MOD_RES 365 365 N6-acetyllysine.
MOD_RES 377 377 N6-acetyllysine.
MOD_RES 388 388 N6-acetyllysine. |
Keyword | Acetylation; Alternative splicing; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 531 AA |
Protein Sequence | MAAVKTLNPK AEVARAQAAL AVNISAARGL QDVLRTNLGP KGTMKMLVSG AGDIKLTKDG 60
NVLLHEMGLH PRIITEGFEA AKEKALQFLE EVKVSREMDR ETLIDVARTS LRTKVHAELA 120
DVLTEAVVDS ILAIKKQDEP IDLFMIEIME MKHKSETDTS LIRGLVLDHG ARHPDMKKRV 180
EDAYILTCNV SLEYEKTEVN SGFFYKSAEE REKLVKAERK FIEDRVKKII ELKRKVCGDS 240
DKGFVVINQK GIDPFSLDAL SKEGIVALRR AKRRNMERLT LACGGVALNS FDDLSPDCLG 300
HAGLVYEYTL GEEKFTFIEK CNNPRSVTLL IKGPNKHTLT QIKDAVRDGL RAVKNAIDDG 360
CVVPGAGAVE VAMAEALIKH KPSVKGRAQL GVQAFADALL IIPKVLAQNS GFDLQETLVK 420
IQAEHSESGQ LVGVDLNTGE PMVAAEVGVW DNYCVKKQLL HSCTVIATNI LLVDEIMRAG 480
MSSLKG 486 |
Gene Ontology | GO:0005832; C:chaperonin-containing T-complex; IEA:Compara. GO:0005829; C:cytosol; TAS:Reactome. GO:0005874; C:microtubule; IDA:UniProtKB. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0051082; F:unfolded protein binding; TAS:ProtInc. GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |