CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025853
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chaperonin containing TCP1, subunit 3 (Gamma) variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
76IRTCLGPKSMMKMLLubiquitination[1]
160VVISAYRKALDDMISubiquitination[1]
413ILLRGASKEILSEVEubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 577 AA 
Protein Sequence
EAAFSGLLSG SLSPEGSAGS PSSGYPALHR VAMMGHRPVL VLSQNTKRES GRKVQSGNIN 60
AAKTIADIIR TCLGPKSMMK MLLDPMGGIV MTNDGNAILR EIQVQHPAAK SMIEISRTQD 120
EEVGDGTTSV IILAGEMLSV AEHFLEQQMH PTVVISAYRK ALDDMISTLK KISIPVDISD 180
SDMMLNIINS SITTKAISRW SSLACNIALD AVKMVQFEEN GRKEIDIKKY ARVEKIPGGI 240
IEDSCVLRGV MINKDVTHPR MRRYIKNPRI VLLDSSLEYK KGESQTDIEI TREEDFTRIL 300
QMEEEYIQQL CEDIIQLKPD VVITEKGISD LAQHYLMRAN ITAIRRVRKT DNNRIARACG 360
ARIVSRPEEL REDDVGTGAG LLEIKKIGDE YFTFITDCKD PKACTILLRG ASKEILSEVE 420
RNLQDAMQVC RNVLLDPQLV PGGGASEMAV AHALTEKSKA MTGVEQWPYR AVAQALEVIP 480
RTLIQNCGAS TIRLLTSLRA KHTQENCETW GVNGETGTLV DMKELGIWEP LAVKLQTYKT 540
AVETAVLLLR IDDIVSGHKK KGDDQSRQGG APDAGQE 577 
Gene Ontology
 GO:0005832; C:chaperonin-containing T-complex; IEA:Compara.
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR012719; Chap_CCT_gamma.
 IPR017998; Chaperone_TCP-1.
 IPR002194; Chaperonin_TCP-1_CS.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial.
 IPR027410; TCP-1-like_intermed. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00750; TCP1_1
 PS00751; TCP1_2
 PS00995; TCP1_3 
PRINTS
 PR00304; TCOMPLEXTCP1.