| Tag | Content |
|---|
| CPLM ID | CPLM-008853 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phospholipase A-2-activating protein |
Protein Synonyms/Alias | PLA2P; PLAP |
Gene Name | Plaa |
Gene Synonyms/Alias | Plap |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 529 | AYRSAASKTVNIYFP | acetylation | [1] | | 554 | NPTQILGKLKELNGS | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Involved in the maintenance of ubiquitin levels (By similarity). |
Sequence Annotation | REPEAT 17 56 WD 1.
REPEAT 63 107 WD 2.
REPEAT 110 148 WD 3.
REPEAT 149 188 WD 4.
REPEAT 190 227 WD 5.
REPEAT 229 268 WD 6.
REPEAT 270 307 WD 7.
DOMAIN 366 465 PFU.
DOMAIN 533 794 PUL.
REPEAT 546 588 ARM 1.
REPEAT 589 620 ARM 2.
REPEAT 621 669 ARM 3.
REPEAT 670 715 ARM 4.
REPEAT 716 755 ARM 5.
REPEAT 756 795 ARM 6.
MOD_RES 529 529 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Complete proteome; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 795 AA |
Protein Sequence | MASGAARYRL SCSLPGHELD VRGLVCCLYP PGAFVSVSRD RTTRLWAPDS PNRGFTEMHC 60
MSGHSNFVSC VCIIPSSDIY PHGLIATGGN DHNICIFSLD SPMPLYILKG HKDTVCSLSS 120
GKFGTLLSGS WDTTAKVWLN DKCMMTLQGH TAAVWAVKIL PEQGLMLTGS ADKTIKLWKA 180
GRCERTFSGH EDCVRGLAIL SETEFLSCAN DASIRRWQIT GECLGVYYGH TNYIYSISVF 240
PNCRDFVTTA EDRSLRIWKH GECAQTIRLP AQSIWCCCVL DNGDIVVGAS DGIIRVFTEA 300
DERTASAEEI KAFERELSQA TIDSKTGDLG DINAEQLPGR EHLNEPGTRE GQTRLIRDGE 360
RVEAYQWSVS DGRWIKIGDV VGSSGANQQT SGKVLYEGKE FDYVFSIDVN EGGPSYKLPY 420
NVSDDPWLVA YNFLQKNDLN PMFLDQVAKF IIDNTKGQTL GLGNTSFSDP FTGGGRYVPG 480
TSGPSNTVQT ADPFTGAGRY MPGSAGMDTT MAGVDPFTGN SAYRSAASKT VNIYFPKKEA 540
LTFDQANPTQ ILGKLKELNG SAPEEKKLTE DDLVLLEKIL SLICGNASEK PTAQQLQVLW 600
KAINWPEDIV FPALDILRLS IKHPSVNENF CNEKEGDQFS SHLINLLNPK GKPANQLLAL 660
RTFCNCFVSQ AGQKLMMSQR ESLMSHAIEL KSGSNKNIHI ALATLTLNYS VCFHKDHNIE 720
GKAQCLSVIS TILEVVQDLE ATFRLLVALG TLISDDSNAI QLAKSLGVDS QIKKYASVSE 780
PAKVSECCRL ILNLL 795 |
Gene Ontology | GO:0070062; C:extracellular vesicular exosome; IEA:Compara. GO:0016005; F:phospholipase A2 activator activity; IEA:Compara. GO:0006954; P:inflammatory response; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |