CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034308
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone demethylase UTY 
Protein Synonyms/Alias
  
Gene Name
 Uty 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
426QKLQSFGKDQQPPFQacetylation[1]
478IPTSEEQKIINFTKEacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 647 AA 
Protein Sequence
MSSSCVHHLR GNEEKKMAAE KARGEGEEGS FSLTVEEKKA LCGLDSSFFG FLTRCKDGAK 60
MKTLLNKAIH FYESLIVKAE GKVESDFFCQ LGHFNLLLED YSKALSSYQR YYSLQTDYWK 120
NAAFLYGLGL VYFYYNAFQW AIRAFQEVLY VDPNFCRAKE IHLRLGFMFK MNTDYESSLK 180
HFQLALIDCN VCTLSSVEIQ FHIAHLYETQ RKYHSAKAAY EQLLQIESLP SQVKATVLQQ 240
LGWMHHNMDL IGDNTTKERY AIQYLQKSLE EDPNSGQSWY FLGRCYSCIG KVQDAFVSYR 300
QSIDKSEASA DTWCSIGVLY QQQNQPMDAL QAYICAVQLD HGHAAAWMDL GILYESCNQP 360
QDAIKCYLNA ARSKSCNNTS ALTSRIKFLQ SVSDTWNSVQ TASHHSVQQK VYTQCFTAQK 420
LQSFGKDQQP PFQTGSTRYL QAASTNDQNQ NGNHTLPQNS KGDAQNHFLR IPTSEEQKII 480
NFTKESKDSR SKSLTSKTSR KDRDTSNICV NAKKHSNHIY QISSVPISSL NNKESVSPDL 540
IIVDNPQLSV LVGETIDNVD HDIGTCDKVN NVHLAIHKKP DNLSASSPSS AISTETLSLK 600
LTEQTHIVTS FISPHSGLHT INGEGHENLE SSASVNVGLR PRSQIIP 647 
Gene Ontology
 GO:0051864; F:histone demethylase activity (H3-K36 specific); IMP:MGI.
 GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:MGI.
 GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:MGI.
 GO:0086003; P:cardiac muscle cell contraction; IMP:MGI.
 GO:0045184; P:establishment of protein localization; IDA:MGI.
 GO:0007507; P:heart development; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0031935; P:regulation of chromatin silencing; IMP:MGI. 
Interpro
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF13181; TPR_8 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS