| Tag | Content |
|---|
| CPLM ID | CPLM-021482 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cation channel sperm-associated protein subunit beta |
Protein Synonyms/Alias | CatSper-beta |
Gene Name | CATSPERB |
Gene Synonyms/Alias | C14orf161 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 57 | YLFLENLKIQCFFQT | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (By similarity). |
Sequence Annotation | CARBOHYD 90 90 N-linked (GlcNAc...) (Potential).
CARBOHYD 100 100 N-linked (GlcNAc...) (Potential).
CARBOHYD 118 118 N-linked (GlcNAc...) (Potential).
CARBOHYD 226 226 N-linked (GlcNAc...) (Potential).
CARBOHYD 321 321 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Complete proteome; Developmental protein; Differentiation; Glycoprotein; Membrane; Polymorphism; Reference proteome; Spermatogenesis; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1116 AA |
Protein Sequence | MESPLIYVSV LLLNIFEFSS GIVYNKDDTE KRFACSNKGF PQENEIIKLY LFLENLKIQC 60
FFQTENEIAS KAMLSVFTSG GLAPSLGIMN STYNGIFHFN LTLFSDRILW LVDIPRENIT 120
QSTDIAAVEE WLVRITLHHG LNIYATEGTL LDVIREPILQ WTPGDVIPES EISKLYPHVV 180
DLKVTKCPCA NDVALLGFIV DTIVDGVYIG ITFGGFWHDY DTTWFNMTQT IYSQLQEEYE 240
DLSLVDMVLT NHFLVILTSL GLFVSEDLRY PSRHSLSFSR ADFCGFERVD YVKGKLWYNE 300
RCFANREHFE VDYVTVTFER NRTLSESSSC FYSQEPFLEW VPCLPHIFKG IKIFPTVLTF 360
LVDQERGTGV YLFYNKVRKT AIASVSTLRN NEPNSQSKFP IFRFPSSFSS PVGMVFHPRS 420
HFLYAYGNQI WLSVDGGNTF QLIANFHDDI IKKTFHSFYT SAITFVSQRG KVYSTKAGMG 480
RYSAVGSVTE RIFTLYYDHL GFLHKLTLGR FEASGPPTAF GNSRNLFGQP PDMGFETALA 540
PQHTSLDEII FFAYVPENEP QETIYSKKFG NIHYGKVIHS GKTGRAYIRK VLQHTTPKGF 600
LSSVIAEMKE PFGLEEVNES SCLSSSLLIN KAGNVYKLTL DSQVVQALFE DTDIEKTVVL 660
PGYSSFLITS ILDNKNALAI ATMPESAPNN MTFLKSTWFL YNFGQRNGRT WKIYSKPCNY 720
WFQHDDSPSL NIVKYIDLGN SYVLKAKVIR NAKGFRMLEI PLLTVFVGNP NLLEVTAEVT 780
FDDTDSYVIT ISAASKVLHQ GSTSLAFIMW SASTECFVTT MVPTLKSSCS YLRSMHHIPS 840
KFIPFEDWIS GVHKDSQGFN LIKTLPINYR PPSNMGIAIP LTDNFYHADP SKPIPRNMFH 900
MSKKTGKFKQ CANVSTREEC NCTKDQKFSH AVAFSDCREK VPRFKFPITQ YPVSLEIINE 960
DGRVPLQSPY LVTVTEVNMR HNWKLKHTVP ENIKRMKQLV EPILGAAVYN PSGLNLSIKG 1020
SELFHFRVTV ISGVTFCNLI EEFQIYVDEA PLPFPGHTLI AVATAVVLGG LIFIAFMFQL 1080
QGIHPWRTFQ RWIRRNQEKF SSISLSELIH RSKSEE 1116 |
Gene Ontology | GO:0036128; C:CatSper complex; ISS:UniProtKB. GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |