UniProt Accession

 CYB5B_RAT; P04166; Q9QWG1 

Genbank Protein ID

 Y12517; BC072535 

Genbank Nucleotide ID

 CAA73117.1; AAH72535.1 

Protein Name

 Cytochrome b5 type B 

Protein Synonyms/Alias

 Cytochrome b5 outer mitochondrial membrane isoform 

Gene Name

 Cyb5b 

Gene Synonyms/Alias

 Cyb5m; Omb5 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
30	YRLEEVAKRNTAEET	acetylation	[1]
88	PDAREMLKQYYIGDV	acetylation	[1]
101	DVHPNDLKPKDGDKD	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. 

Sequence Annotation

 DOMAIN 20 96 Cytochrome b5 heme-binding.
 METAL 55 55 Iron (heme axial ligand).
 METAL 79 79 Iron (heme axial ligand).
 MOD_RES 30 30 N6-acetyllysine (By similarity).  

Keyword

 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Electron transport; Heme; Iron; Membrane; Metal-binding; Mitochondrion; Mitochondrion outer membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 146 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0005741; C:mitochondrial outer membrane; IDA:RGD.
 GO:0045153; F:electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity; TAS:RGD.
 GO:0008047; F:enzyme activator activity; IDA:RGD.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. 

Interpro

 IPR001199; Cyt_B5-like_heme/steroid-bd.
 IPR018506; Cyt_B5_heme-BS. 

Pfam

 PF00173; Cyt-b5 

SMART

  

PROSITE

 PS00191; CYTOCHROME_B5_1
 PS50255; CYTOCHROME_B5_2 

PRINTS

 PR00363; CYTOCHROMEB5.