CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009291
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cyclin-dependent kinases regulatory subunit 1 
Protein Synonyms/Alias
 CKS-1; Sid 1334 
Gene Name
 Cks1b 
Gene Synonyms/Alias
 Cks1; Sid1334 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
4****MSHKQIYYSDKacetylation[1, 2]
11KQIYYSDKYDDEEFEacetylation[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
 Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function (By similarity). 
Sequence Annotation
  
Keyword
 Cell cycle; Cell division; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 79 AA 
Protein Sequence
MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ SQGWVHYMIH 60
EPEPHILLFR RPLPKKPKK 79 
Gene Ontology
 GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW. 
Interpro
 IPR000789; Cyclin-dep_kinase_reg-sub. 
Pfam
 PF01111; CKS 
SMART
 SM01084; CKS 
PROSITE
 PS00944; CKS_1
 PS00945; CKS_2 
PRINTS
 PR00296; CYCLINKINASE.