| Tag | Content |
|---|
| CPLM ID | CPLM-013161 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein Niban |
Protein Synonyms/Alias | Protein FAM129A |
Gene Name | Fam129a |
Gene Synonyms/Alias | Niban |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 563 | ITEAAILKKHNLFED | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response. |
Sequence Annotation | MOD_RES 578 578 Phosphoserine.
MOD_RES 595 595 Phosphoserine (By similarity).
MOD_RES 601 601 Phosphoserine.
MOD_RES 640 640 Phosphoserine (By similarity).
MOD_RES 755 755 Phosphoserine.
MOD_RES 923 923 Phosphoserine (By similarity). |
Keyword | Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Stress response; Translation regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 926 AA |
Protein Sequence | MGGSASSQLD EGKCAYIRGK TEASIKNFSP YYSRQYSVAF CNHVRSEVEQ QRDLTSQFLK 60
TKPPLEPGTV LYEAELSQFA EDIRKWKDRY IVIKNDFAVE SYESKEAYQR GAVPKSRILP 120
AGGKVLTSEE EYSLLSDKHF PDPTASSEKN SQPFVLLPKA FPVYLWQPYL RHGYFCFHEA 180
AEQQKFSALL NDCIRHLNHD YMKQTTFEAQ AFLEAVQFFR QEKGHYGSWE MTTGDEVQVL 240
SKLVMEELLP TLQTDLLPKL KGKKNDRKRA WFGLLEEAYN LVQHQVSEGL NALKEECRAL 300
TKDLEGTIRS DMDQIVTSKN FLTGKIRAMV AQPAEQCCGE SVQPFLASIL EELMGPVSSG 360
FSEVRALFEK EVDELSQSFH ATQDSAQLKE GLQQLMKLPL DSVKMEPCYT KVTLLPERLL 420
DLQSRFRFPH VDLVVQRTQN YMQELMENAV FTFEQLLSPY LQGEASRIPV AIEKVKLRVL 480
KQYDYDSSTI RKKIFQEALI QITLPTVQKA LASTCKPELQ KYEQFIFADH TNMIHVENVY 540
EEILYEILLD ETLKVITEAA ILKKHNLFED NMALPSESVS SLTDLKTAMG SNQASPARRV 600
SAILPGAPDN ELPSNEVFQE PEEKKEQPGV PGSLAISASS CPSGGDGQVS VDHSAGGPLT 660
VENTAGPLSS HLSEVEAGGT LKDEEPTCQS PEPSAVPGSL KELKKLLTVT VSVESAPVVE 720
NDIHNGTPVP QENIKEEESK IHPEASHPAA IQQDSCEERE VREKEAQPLE AEAPGVDLGI 780
LPEGRGSTSQ STSGGLTENT SCPGPIEEPF EAQEPAEKVL PAIVSTEDSP QAGGEAEHSV 840
TVTPQEDATL SSNPICPMES NEVAQASGDQ EVLGGEDSSA LGMDTEQVND THEHACQWLV 900
EDTLSTDILA VHDFDVSSPE QPSEEW 926 |
Gene Ontology | GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0005634; C:nucleus; IEA:Compara. GO:0005886; C:plasma membrane; IEA:Compara. GO:0001933; P:negative regulation of protein phosphorylation; IMP:UniProtKB. GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB. GO:0045727; P:positive regulation of translation; IMP:UniProtKB. GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |