CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037141
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger protein 638 
Protein Synonyms/Alias
  
Gene Name
 ZNF638 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
370RDQINAEKKLSAKEFubiquitination[1]
381AKEFGLLKPTSARSGacetylation[2]
806GKTLPSEKAVVTEPAacetylation[3]
898RHKQNTEKFMAKQRKacetylation[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 918 AA 
Protein Sequence
MDSPPLKALN SNSIYFLLLF HCMLISEVQI EHDPELEKES PGLKNSPIDE SEVQTATDSP 60
SVKPNELEEE STPSIQTETL VQQEEPCEEE AEKATCDSDF AVETLELETQ GEEVKEEIPL 120
VASASVSIEQ FTENAEECAL NQQMFNSDLE KKGAEIINPK TALLPSDSVF AEERNLKGIL 180
EESPSEAEDF ISGITQTMVE AVAEVEKNET VSEILPSTCI VTLVPGIPTG DEKTVDKKNI 240
SEKKGNMDEK EEKEFNTKET RMDLQIGTEK AEKNEGRMDA EKVEKMAAMK EKPAENTLFK 300
AYPNKGVGQA NKPDETSKTS ILAVSDVSSS KPSIKAVIVS SPKAKATVSK TENQKSFPKS 360
VPRDQINAEK KLSAKEFGLL KPTSARSGLA ESSSKFKPTQ SSLTRGGSGR ISALQGKLSK 420
LDYRDITKQS QETEARPSIM KRDDSNNKTL AEQNTKNPKS TTGRSSKSKE EPLFPFNLDE 480
FVTVDEVIEE VNPSQAKQNP LKGKRKETLK NVPFSELNLK KKKGKTSTPR GVEGELSFVT 540
LDEIGEEEDA AAHLAQALVT VDEVIDEEEL NMEEMVKNSN SLFTLDELID QDDCISHSEP 600
KDVTVLSVAE EQDLLKQERL VTVDEIGEVE ELPLNESADI TFATLNTKGN EGDTVRDSIG 660
FISSQVPEDP STLVTVDEIQ DDSSDLHLVT LDEVTEEDED SLADFNNLKE ELNFVTVDEV 720
GEEEDGDNDL KVELAQSKND HPTDKKGNRK KRAVDTKKTK LESLSQVGPV NENVMEEDLK 780
TMIERHLTAK TPTKRVRIGK TLPSEKAVVT EPAKGEEAFQ MSEVDEESGL KDSEPERKRK 840
KTEDSSSGKS VASDVPEELD FLVPKAGFFC PICSLFYSGE KAMTNHCKST RHKQNTEKFM 900
AKQRKEKEQN EAEERSSR 918 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR000690; Znf_C2H2_matrin.
 IPR003604; Znf_U1. 
Pfam
  
SMART
 SM00355; ZnF_C2H2
 SM00451; ZnF_U1 
PROSITE
 PS50171; ZF_MATRIN
 PS00028; ZINC_FINGER_C2H2_1 
PRINTS