CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024735
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Spermatid-specific linker histone H1-like protein 
Protein Synonyms/Alias
  
Gene Name
 Hils1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
49LRKPTMSKVILRTVAacetylation[1]
70RVSLAALKKAVSITGacetylation[1]
158KSNNRLFKGVRRVAKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa (By similarity). 
Sequence Annotation
 DOMAIN 43 116 H15.  
Keyword
 Chromatin regulator; Chromosome; Complete proteome; Developmental protein; Differentiation; DNA-binding; Nucleus; Reference proteome; Spermatogenesis; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 169 AA 
Protein Sequence
MSLVSPSPDS NAVMAGDQDA STSQVPSQSE SKIGPNVATQ TLRKPTMSKV ILRTVADKGV 60
HSRVSLAALK KAVSITGYNM AQNTWRFKRV LQNLVKKGML KQVTGKGASG SFRLGKKQAF 120
KSKCKAKRRQ RRQKPGQRRT GSRRSLLGSK KSNNRLFKGV RRVAKGRRH 169 
Gene Ontology
 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR005818; Histone_H1/H5.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00538; Linker_histone 
SMART
 SM00526; H15 
PROSITE
 PS51504; H15 
PRINTS