Tag | Content |
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CPLM ID | CPLM-003251 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Anti-adapter protein IraP |
Protein Synonyms/Alias | |
Gene Name | iraP |
Gene Synonyms/Alias | yaiB; b0382; JW0373 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
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15 | LLFKLAQKEEESKEL | acetylation | [1] | 60 | EGALYEVKPDASIPD | acetylation | [1] |
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Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. |
Sequence Annotation | |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Reference proteome; Stress response. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 86 AA |
Protein Sequence | MKNLIAELLF KLAQKEEESK ELCAQVEALE IIVTAMLRNM AQNDQQRLID QVEGALYEVK 60 PDASIPDDDT ELLRDYVKKL LKHPRQ 86 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0043856; F:anti-sigma factor antagonist activity; IDA:EcoCyc. GO:0016036; P:cellular response to phosphate starvation; IMP:EcoCyc. GO:0042177; P:negative regulation of protein catabolic process; IDA:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |