CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016580
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C 
Protein Synonyms/Alias
 PP6-ARS-C; Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C 
Gene Name
 Ankrd52 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
121AAANRATKCAEALAPubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
 Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates (By similarity). 
Sequence Annotation
 REPEAT 7 36 ANK 1.
 REPEAT 40 69 ANK 2.
 REPEAT 73 102 ANK 3.
 REPEAT 106 135 ANK 4.
 REPEAT 139 168 ANK 5.
 REPEAT 172 201 ANK 6.
 REPEAT 205 234 ANK 7.
 REPEAT 238 267 ANK 8.
 REPEAT 271 301 ANK 9.
 REPEAT 305 334 ANK 10.
 REPEAT 338 367 ANK 11.
 REPEAT 371 400 ANK 12.
 REPEAT 422 451 ANK 13.
 REPEAT 455 484 ANK 14.
 REPEAT 488 545 ANK 15.
 REPEAT 549 579 ANK 16.
 REPEAT 584 613 ANK 17.
 REPEAT 617 646 ANK 18.
 REPEAT 651 680 ANK 19.
 REPEAT 687 716 ANK 20.
 REPEAT 720 749 ANK 21.
 REPEAT 753 782 ANK 22.
 REPEAT 790 819 ANK 23.
 REPEAT 822 852 ANK 24.
 REPEAT 857 886 ANK 25.
 REPEAT 890 920 ANK 26.
 REPEAT 924 953 ANK 27.
 REPEAT 960 989 ANK 28.
 MOD_RES 1028 1028 Phosphoserine (By similarity).  
Keyword
 ANK repeat; Complete proteome; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1076 AA 
Protein Sequence
MGILSITDQP PLVQAIFSRD VEEVRSLLSQ KENINVLDQE RRTPLHAAAY VGDVPILQLL 60
LMSGANVNAK DTLWLTPLHR AAASRNEKVL GLLLAHSADV NARDKLWQTP LHVAAANRAT 120
KCAEALAPLL SSLNVADRSG RSALHHAVHS GHLETVNLLL NKGASLNVCD KKERQPLHWA 180
AFLGHLEVLK LLVARGADLS CKDRKGYGLL HTAAASGQIE VVKHLLRMGA EIDEPNAFGN 240
TALHIACYLG QDAVAIELVN AGANVNQPND KGFTPLHVAA VSTNGALCLE LLVNNGADVN 300
YQSKEGKSPL HMAAIHGRFT RSQILIQNGS EIDCADKFGN TPLHVAARYG HELLISTLMT 360
NGADTARRGI HDMFPLHLAV LFGFSDCCRK LLSSGQLYSI VSSLSNEHVL SAGFDINTPD 420
SLGRTCLHAA ASGGNVECLN LLLSSGADLR RRDKFGRTPL HYAAANGSYQ CAVTLVTAGA 480
GVNEADCKGC SPLHYAAASD TYRRAEPHTA SSHDAEEDEL LKESRRKEAF FCLEFLLDNG 540
ADPSLRDRQG YTAVHYAAAY GNRQNLELLL EMSFNCLEDV ESTVPVSPLH LAAYNGHCEA 600
LKTLAETLVN LDVRDHKGRT ALFLATERGS TECVEVLTAH GASALIKERK RKWTPLHAAA 660
ASGHTDSLHL LIDSGERADI TDVMDAYGQT PLMLAIMNGH VDCVHLLLEK GSTADAADLR 720
GRTALHRGAV TGCEDCLAAL LDHDAFVLCR DFKGRTPIHL ASACGHTAVL RTLLQAALST 780
DPLDAGVDYS GYSPMHWASY TGHEDCLELL LEHSPFSYLE GNPFTPLHCA VINNQDSTTE 840
MLLGALGAKI VNSRDAKGRT PLHAAAFADN VSGLRMLLQH QAEVNATDHT GRTALMTAAE 900
SGQTAAVEFL LYRGKADLTV LDENKNTALH LACSKGHEKC ALMILAETQD LGLINATNSA 960
LQMPLHIAAR NGLASVVQAL LSRGATVLAV DEEGHTPALA CAPNKDVADC LALILSTMKP 1020
FPPKDAVSPF SFSLLKNCGI AAAKTVGGCG ALPHGASCPY SQERHGAIGL DGCYSE 1076 
Gene Ontology
  
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF00023; Ank
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS
 PR01415; ANKYRIN.