Tag | Content |
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CPLM ID | CPLM-004101 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alanine aminotransferase 1 |
Protein Synonyms/Alias | ALT1; Glutamate pyruvate transaminase 1; GPT 1; Glutamic--alanine transaminase 1; Glutamic--pyruvic transaminase 1 |
Gene Name | GPT |
Gene Synonyms/Alias | AAT1; GPT1 |
Created Date | July 27, 2013 |
Organism | Sus scrofa (Pig) |
NCBI Taxa ID | 9823 |
Lysine Modification | Position | Peptide | Type | References |
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11 | ASFHSVSKGFMGECG | glycation | [1] |
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Reference | [1] Inhibitory effect of glycation on catalytic activity of alanine aminotransferase. Beránek M, Drsata J, Palicka V. Mol Cell Biochem. 2001 Feb;218(1-2):35-9. [ PMID: 11330835] |
Functional Description | Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity). |
Sequence Annotation | MOD_RES 11 11 N6-(pyridoxal phosphate)lysine. CARBOHYD 11 11 N-linked (Glc) (glycation); in vitro. |
Keyword | Aminotransferase; Complete proteome; Cytoplasm; Direct protein sequencing; Glycation; Glycoprotein; Pyridoxal phosphate; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 20 AA |
Protein Sequence | QELASFHSVS KGFMGECGFR 20 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004021; F:L-alanine:2-oxoglutarate aminotransferase activity; IEA:EC. GO:0042853; P:L-alanine catabolic process; IEA:UniProtKB-UniPathway. |
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