CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035539
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Ank2 
Protein Synonyms/Alias
  
Gene Name
 Ank2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
61ARAGNLDKVVEYLKGubiquitination[1]
397CGHYRVTKLLLDKRAacetylation[2]
402VTKLLLDKRANPNARacetylation[2]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 453 AA 
Protein Sequence
MAHAAASIKK VREAELDEKE KNLERERKKQ RKIPRDRMER KRKSDSNASF LRAARAGNLD 60
KVVEYLKGGI DINTCNQNGL NALHLAAKEG HVGLVQELLG RGSSVDSATK KGNTALHIAS 120
LAGQAEVVKV LVKEGANINA QSQNGFTPLY MAAQENHIDV VKYLLENGAN QSTATEDGFT 180
PLAVALQQGH NQAVAILLEN DTKGKVRLPA LHIAARKDDT KSAALLLQND HNADVQSKMM 240
VNRTTESGFT PLHIAAHYGN VNVATLLLNR GAAVDFTARN GITPLHVASK RGNTNMVKLL 300
LDRGGQIDAK TRDGLTPLHC AARSGHDQVV ELLLERGAPL LARTKNGLSP LHMAAQGDHV 360
ECVKHLLQHK APVDDVTLDY LTALHVAAHC GHYRVTKLLL DKRANPNARA LVNLAQSTFA 420
NYHKTTLLGQ WHLHQSKSID SQSIAKFPPP LNH 453 
Gene Ontology
 GO:0005856; C:cytoskeleton; IDA:RGD.
 GO:0045121; C:membrane raft; IDA:RGD.
 GO:0043005; C:neuron projection; IDA:RGD.
 GO:0005886; C:plasma membrane; IDA:RGD.
 GO:0005200; F:structural constituent of cytoskeleton; IDA:RGD.
 GO:0030913; P:paranodal junction assembly; IEP:RGD.
 GO:0051597; P:response to methylmercury; IEP:RGD. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS
 PR01415; ANKYRIN.