CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024321
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Oxysterol-binding protein-related protein 9 
Protein Synonyms/Alias
 ORP-9; OSBP-related protein 9 
Gene Name
 Osbpl9 
Gene Synonyms/Alias
 Orp9 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
615EIFSPNDKKSFCSIEubiquitination[1]
645NTVFVDTKKLPIIKKacetylation[2]
677KDVTFNLKIRDIDAAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
 DOMAIN 2 99 PH.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 326 326 Phosphoserine.  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Lipid transport; Lipid-binding; Phosphoprotein; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 736 AA 
Protein Sequence
MASIVEGPLS KWTNVMKGWQ YRWFVLDYNA GLLSYYTSKD KMMRGSRRGC VRLRGAVIGI 60
DDEDDSTFTI TVDQKTFHFQ ARDADEREKW IHALEETILR HTLQLQGLDS GFIPSVQDFD 120
KKLTEADAYL QILIEQLKLF DDKLQNCKDD EQRKKVETLK DTTNSMVESI KHCIVLLQIA 180
KDQSNAEQHA DGIISTINPV DAIYQPSPLE PVISTMPSQT ALPPEPAQLC KSEQRPSSLP 240
VGPVLATLGH HQTPTPNSTG SGNSPPSSSL TPPSHVNLSP NTVPEFSYSS SEDEFYDADE 300
FHQSGSSPKR LIDSSGSASV LTHSSSGNSL KRPDTTESLN SSMSNGTSDA DLFDSHDDRD 360
DDGEAGSVEE HKSVIMHLLS QVRLGMDLTK VVLPTFILER RSLLEMYADF FAHPDLFVSI 420
SDQKDPRDRM VQVVKWYLSA FHAGRRGSVA KKPYNPILGE IFQCHWTLPN DTEENAELVS 480
EGPVPWVSKN SVTFVAEQVS HHPPISAFYA ECFNKKIQFN AHIWTKSKFL GMSIGVHNIG 540
QGCVSCLEYD EHYILTFPNG YGRSILTVPW VELGGECNIN CSKTGYSANI VFHTKPFYGG 600
KKHRITAEIF SPNDKKSFCS IEGEWNGIMY AKYATGENTV FVDTKKLPII KKKVRKLEDQ 660
NEYESRSLWK DVTFNLKIRD IDAATEAKHR LEERQRAEAR ERKEKEIQWE TRLFHEDGEC 720
WVYDEPLLKR LGAVKH 736 
Gene Ontology
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0006869; P:lipid transport; IEA:UniProtKB-KW. 
Interpro
 IPR000648; Oxysterol-bd.
 IPR018494; Oxysterol-bd_CS.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF01237; Oxysterol_BP
 PF00169; PH 
SMART
 SM00233; PH 
PROSITE
 PS01013; OSBP
 PS50003; PH_DOMAIN 
PRINTS