UniProt Accession

 KDPE_ECOLI; P21866; P75739; P76822 

Genbank Protein ID

 M36066; U00096; AP009048 

Genbank Nucleotide ID

 AAA24042.1; AAC73788.1; BAA35351.2 

Protein Name

 KDP operon transcriptional regulatory protein KdpE 

Protein Synonyms/Alias

  

Gene Name

 kdpE 

Gene Synonyms/Alias

 b0694; JW5096 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
87	ARSEESDKIAALDAG	acetylation	[1]
101	GADDYLSKPFGIGEL	acetylation	[1]
130	TAPDPLVKFSDVTVD	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Member of the two-component regulatory system KdpD/KdpE involved in the regulation of the kdp operon. 

Sequence Annotation

 DOMAIN 1 116 Response regulatory.
 MOD_RES 52 52 4-aspartylphosphate (By similarity).  

Keyword

 3D-structure; Complete proteome; Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Two-component regulatory system. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 225 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0000986; F:bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding; IDA:EcoCyc.
 GO:0001131; F:bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:EcoCyc.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:GOC. 

Interpro

 IPR011006; CheY-like_superfamily.
 IPR001867; Sig_transdc_resp-reg_C.
 IPR001789; Sig_transdc_resp-reg_receiver.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00072; Response_reg
 PF00486; Trans_reg_C 

SMART

 SM00448; REC
 SM00862; Trans_reg_C 

PROSITE

 PS50110; RESPONSE_REGULATORY 

PRINTS