CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043135
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Isovaleryl-CoA dehydrogenase, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 IVD 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39ELRQTMAKFLQEHLAubiquitination[1]
59IDRSNEFKNLREFWKacetylation[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 212 AA 
Protein Sequence
MVFWWRIGQA TYRLWHKGPQ SVCSSLTPEQ AELRQTMAKF LQEHLAPKAQ EIDRSNEFKN 60
LREFWKQLGN LGVLGITAPV QYGGSGLGYL EHVLVMEEIS RASGAVGLSY GAHSNLCINQ 120
LVRNGNEAQK EKYLPKLISG EYIGALAMSE PNAGSDVVSM KLKAEKKGNH YILNGNKFWI 180
TNGPDADVLI VYAKTDLAAV PASRGITAFI VE 212 
Gene Ontology
 GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. 
Interpro
 IPR006089; Acyl-CoA_DH_CS.
 IPR006092; Acyl-CoA_DH_N.
 IPR006091; Acyl-CoA_Oxase/DH_cen-dom.
 IPR013786; AcylCoA_DH/ox_N.
 IPR009100; AcylCoA_DH/oxidase. 
Pfam
 PF02770; Acyl-CoA_dh_M
 PF02771; Acyl-CoA_dh_N 
SMART
  
PROSITE
 PS00072; ACYL_COA_DH_1 
PRINTS