UniProt Accession

 PPIP2_HUMAN; Q9H939 

Genbank Protein ID

 AC012569; AC090355; BC035395; AK023100 

Genbank Nucleotide ID

 AAH35395.1; BAB14404.1 

Protein Name

 Proline-serine-threonine phosphatase-interacting protein 2 

Protein Synonyms/Alias

 PEST phosphatase-interacting protein 2 

Gene Name

 PSTPIP2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
176	QQEKLFVKLATSKTA	ubiquitination	[1]
181	FVKLATSKTAVEDSD	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Binds to F-actin. May be involved in regulation of the actin cytoskeleton (By similarity). 

Sequence Annotation

 DOMAIN 4 89 FCH.
 MOD_RES 323 323 Phosphotyrosine (By similarity).
 MOD_RES 329 329 Phosphotyrosine (By similarity).  

Keyword

 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Membrane; Phosphoprotein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 334 AA 

Protein Sequence

Gene Ontology

 GO:0005856; C:cytoskeleton; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0016020; C:membrane; IEA:UniProtKB-SubCell. 

Interpro

 IPR001060; FCH_dom. 

Pfam

 PF00611; FCH 

SMART

 SM00055; FCH 

PROSITE

 PS50133; FCH 

PRINTS