CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021336
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription elongation factor A protein-like 2 
Protein Synonyms/Alias
 TCEA-like protein 2; Transcription elongation factor S-II protein-like 2 
Gene Name
 TCEAL2 
Gene Synonyms/Alias
 My048; MY0876G0 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
154AQYLKQYKEAIHDMNubiquitination[1, 2, 3, 4]
Reference
 [1] Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.
 Danielsen JM, Sylvestersen KB, Bekker-Jensen S, Szklarczyk D, Poulsen JW, Horn H, Jensen LJ, Mailand N, Nielsen ML.
 Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. [PMID: 21139048]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [4] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 227 AA 
Protein Sequence
MEKLFNENEG MPSNQGKIDN EEQPPHEGKP EVACILEDKK LENEGNTENT GKRVEEPLKD 60
KEKPESAGKA KGEGKSERKG KSEMQGGSKT EGKPERGGRA EGEGEPDSER EPESEGEPES 120
ETRAAGKRPA EDDIPRKAKR KTNKGLAQYL KQYKEAIHDM NFSNEDMIRE FDNMARVEDK 180
RRKSKQKLGA FLWMQRNLQD PFYPRGPREF RGGCRAPRRD TEDIPYV 227 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR021156; TF_A-like/BEX-like.
 IPR010370; TFA. 
Pfam
 PF04538; BEX 
SMART
  
PROSITE
  
PRINTS