CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002130
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Parathymosin 
Protein Synonyms/Alias
 Zinc-binding 11.5 kDa protein 
Gene Name
 Ptms 
Gene Synonyms/Alias
 Znbp 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
4****MSEKSVEAAAEacetylation[1]
15AAAELSAKDLKEKKDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections. 
Sequence Annotation
 MOD_RES 2 2 N-acetylserine.
 MOD_RES 4 4 N6-acetyllysine (By similarity).
 MOD_RES 5 5 Phosphoserine (By similarity).
 MOD_RES 15 15 N6-acetyllysine (By similarity).
 MOD_RES 92 92 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Complete proteome; Direct protein sequencing; Immunity; Phosphoprotein; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 102 AA 
Protein Sequence
MSEKSVEAAA ELSAKDLKEK KDKVEEKAGR KERKKEVVEE EENGAEEEEE ETAEDGEDDD 60
EGDEEDEEEE EEEDEGPVRK RTAEEEDEAD PKRQKTENGA SA 102 
Gene Ontology
 GO:0005829; C:cytosol; IDA:RGD.
 GO:0004857; F:enzyme inhibitor activity; TAS:RGD.
 GO:0008270; F:zinc ion binding; IDA:RGD. 
Interpro
 IPR004931; Pro/parathymosin. 
Pfam
 PF03247; Prothymosin 
SMART
  
PROSITE
  
PRINTS