UniProt Accession

 Q5TA95_HUMAN; Q5TA95 

Genbank Protein ID

 AL139244; CH471059 

Genbank Nucleotide ID

 EAX06670.1 

Protein Name

 Tetratricopeptide repeat domain 4, isoform CRA_a 

Protein Synonyms/Alias

 Tetratricopeptide repeat protein 4 

Gene Name

 TTC4 

Gene Synonyms/Alias

 hCG_32473 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
52	RWFLEFEKVPLFMSR	ubiquitination	[1]
238	EALLQAIKARNIRLS	ubiquitination	[1, 2]
354	ELYRVPAKSTLLQVL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 398 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 

Pfam

  

SMART

 SM00028; TPR 

PROSITE

 PS50293; TPR_REGION 

PRINTS