| Tag | Content |
|---|
| CPLM ID | CPLM-011074 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar protein-sorting-associated protein 60 |
Protein Synonyms/Alias | Charged multivesicular body protein 5 |
Gene Name | VPS60 |
Gene Synonyms/Alias | CHM5; MOS10; YDR486C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 122 | KQTNNAMKAQYGKIN | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Has a role in a late stage of multivesicular body (MVB) formation. Can stimulate VPS4 ATPase activity via VTA1. |
Sequence Annotation | REGION 128 159 Interaction with VTA1.
MOD_RES 12 12 Phosphoserine. |
Keyword | 3D-structure; Coiled coil; Complete proteome; Endosome; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport; Vacuole. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 229 AA |
Protein Sequence | MNRIFGYGNK KSHDQLLQES NQSMNQAQQS LSNRISQLDT QIAQLNFQLQ NIQKNLQRSN 60
NKQPSLRKQA LKILNKRKQL ENMKDSLDSQ SWSMTQAQLT NDNLQNTMIT INALKQTNNA 120
MKAQYGKINI DKLQDMQDEM LDLIEQGDEL QEVLAMNNNS GELDDISDAE LDAELDALAQ 180
EDFTLPTSEN SLGNDMPSYL LGANAPPAFI DEEPNLDTED KNKALESAQ 229 |
Gene Ontology | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. GO:0000329; C:fungal-type vacuole membrane; IDA:SGD. GO:0030447; P:filamentous growth; IMP:SGD. GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IGI:SGD. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |