CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026673
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 3-hydroxyisobutyrate dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 RPA3446 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
253KLSQEAAKAAGASTPacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 295 AA 
Protein Sequence
MTDIAFIGLG NMGGPMAGNL AKAGRKVAGF DLVAASCEAA KAEGVTIAPT AIDAVKGAGV 60
IVTMLPAGKH VLAVWNEILP HAAKGALIID CSTIDVESAV QAHALATKHD IASVDAPVSG 120
GTGGAKGATL TFMAGGSEAA FAAAKPVLEQ MGKKIVHCGG AGAGQAAKIC NNMILGISMI 180
GVSEAFTLAE KLGLSHQALF DVASTSSGQC WSLTSYCPVP GPVPASPANN SYKPGFAAAL 240
MLKDLKLSQE AAKAAGASTP LGQHAAEIYA AFEQAGHGGT DFSGIINYLR EQGRK 295 
Gene Ontology
 GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
 GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
 GO:0006573; P:valine metabolic process; IEA:InterPro. 
Interpro
 IPR002204; 3-OH-isobutyrate_DH-rel_CS.
 IPR008927; 6-PGluconate_DH_C-like.
 IPR006115; 6PGDH_NADP-bd.
 IPR013328; DH_multihelical.
 IPR015815; HIBADH-type.
 IPR011548; IsoBut3OH_DH.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF03446; NAD_binding_2 
SMART
  
PROSITE
 PS00895; 3_HYDROXYISOBUT_DH 
PRINTS