CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013177
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Plastin-1 
Protein Synonyms/Alias
  
Gene Name
 Pls1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
532KWVNQTLKSANKSTSubiquitination[1]
586EDKLNNAKYAISVARubiquitination[1]
610PDDLVEVKPKMVMTVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Actin-bundling protein in the absence of calcium (By similarity). 
Sequence Annotation
 DOMAIN 11 46 EF-hand 1.
 DOMAIN 51 86 EF-hand 2.
 DOMAIN 108 381 Actin-binding 1.
 DOMAIN 122 238 CH 1.
 DOMAIN 266 377 CH 2.
 DOMAIN 382 626 Actin-binding 2.
 DOMAIN 396 505 CH 3.
 DOMAIN 517 626 CH 4.  
Keyword
 Actin-binding; Calcium; Complete proteome; Cytoplasm; Metal-binding; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 630 AA 
Protein Sequence
MENSTTTISR EELEELQEAF NKIDIDNSGY VSDYELQDLF KEASLPLPGY KVREIVEKIL 60
VVADNNKDGK ISFEEFVSLM QELKSKDISK TFRKIINKRE GITAIGGTSS ISSEGTQHSY 120
SEEEKVAFVN WINKALENDA DCSHLLPMNP NDGSLFKSLA DGILLCKMIN LSEPDTIDER 180
AINKKKLTPF TVSENLNLAL NSASAIGCTV VNIGAQDLKE GKPHLVLGLL WQIIKVGLFA 240
DIEISRNEAL IALLKDGEDL EELMKLSPEE LLLRWVNYHL TNAGWRTINN FSQDIKDSKA 300
YFHLLNQIAP KGDRDDGPAV AIDLSGFNEK NDLKRAGFML QEADKLGCRQ FVTPADVVSG 360
NPKLNLAFVA NLFNTYPCLH KPDNNDIDLN LLEGESKEER TFRNWMNSLG VNPYINHLYS 420
DLADALVIFQ LYEMIRVPVN WSQVNKPPYP ALGGNMKKIE NCNYAVELGK NEAKFSLVGI 480
AGQDLNEGNA TLTLALVWQL MRRYTLKVLS DLGEGEKVTD DIIIKWVNQT LKSANKSTSI 540
SSFKDKSIST SLPVLDLIDA IAPNAVRQEM IKREHLTDED KLNNAKYAIS VARKIGARIY 600
ALPDDLVEVK PKMVMTVFAC LMGKGLNRLK 630 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR001589; Actinin_actin-bd_CS.
 IPR001715; CH-domain.
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF00307; CH
 PF13499; EF_hand_5 
SMART
 SM00033; CH
 SM00054; EFh 
PROSITE
 PS00019; ACTININ_1
 PS00020; ACTININ_2
 PS50021; CH
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS