| Tag | Content |
|---|
| CPLM ID | CPLM-009772 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 7-carboxy-7-deazaguanine synthase |
Protein Synonyms/Alias | CDG synthase; Queuosine biosynthesis protein QueE |
Gene Name | queE |
Gene Synonyms/Alias | ygcF; b2777; JW2748 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 66 | AKTKESDKWGAASSE | acetylation | [1] | | 194 | ALQPISQKDDATRLC | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity). |
Sequence Annotation | METAL 31 31 Iron-sulfur (4Fe-4S-S-AdoMet) (By
METAL 35 35 Iron-sulfur (4Fe-4S-S-AdoMet) (By
METAL 38 38 Iron-sulfur (4Fe-4S-S-AdoMet) (By |
Keyword | 4Fe-4S; Complete proteome; Iron; Iron-sulfur; Lyase; Metal-binding; Queuosine biosynthesis; Reference proteome; S-adenosyl-L-methionine. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 223 AA |
Protein Sequence | MQYPINEMFQ TLQGEGYFTG VPAIFIRLQG CPVGCAWCDT KHTWEKLEDR EVSLFSILAK 60
TKESDKWGAA SSEDLLAVIG RQGYTARHVV ITGGEPCIHD LLPLTDLLEK NGFSCQIETS 120
GTHEVRCTPN TWVTVSPKLN MRGGYEVLSQ ALERANEIKH PVGRVRDIEA LDELLATLTD 180
DKPRVIALQP ISQKDDATRL CIETCIARNW RLSMQTHKYL NIA 223 |
Gene Ontology | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW. GO:0016840; F:carbon-nitrogen lyase activity; IEA:HAMAP. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0008616; P:queuosine biosynthetic process; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |