| Tag | Content |
|---|
| CPLM ID | CPLM-017103 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 440 |
Protein Synonyms/Alias | |
Gene Name | ZNF440 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 48 | TSLGKRWKDQNIEYE | ubiquitination | [1] | | 506 | PVPFDIMKGLTLERS | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 4 86 KRAB.
ZN_FING 144 166 C2H2-type 1; degenerate.
ZN_FING 172 194 C2H2-type 2.
ZN_FING 200 222 C2H2-type 3.
ZN_FING 228 250 C2H2-type 4.
ZN_FING 256 278 C2H2-type 5; degenerate.
ZN_FING 284 306 C2H2-type 6.
ZN_FING 312 334 C2H2-type 7.
ZN_FING 340 362 C2H2-type 8.
ZN_FING 368 390 C2H2-type 9.
ZN_FING 396 418 C2H2-type 10.
ZN_FING 424 448 C2H2-type 11.
ZN_FING 458 480 C2H2-type 12. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 595 AA |
Protein Sequence | MDPVAFKDVA VNFTQEEWAL LDISQRKLYR EVMLETFRNL TSLGKRWKDQ NIEYEHQNPR 60
RNFRSLIEEK VNEIKDDSHC GETFTPVPDD RLNFQEKKAS PEVKSCESFV CGEVGLGNSS 120
FNMNIRGDIG HKAYEYQEYG PKPCKCQQPK KAFRYRPSFR TQERDHTGEK PNACKVCGKT 180
FISHSSVRRH MVMHSGDGPY KCKFCGKAFH CLRLYLIHER IHTGEKPCEC KQCGKSFSYS 240
ATHRIHKRTH TGEKPYEYQE CGKAFHSPRS YRRHERIHMG EKAYQCKECG KAFTCPRYVR 300
IHERTHSRKN LYECKQCGKA LSSLTSFQTH VRLHSGERPY ECKICGKDFC SVNSFQRHEK 360
IHSGEKPYKC KQCGKAFPHS SSLRYHERTH TGEKPYECKQ CGKAFRSASH LRVHGRTHTG 420
EKPYECKECG KAFRYVNNLQ SHERTQTHIR IHSGERRYKC KICGKGFYCP KSFQRHEKTH 480
TGEKLYECKQ RSVVPSVVPV PFDIMKGLTL ERSPINASNV GKPSELCQSF ECMVGLTLKR 540
NPMSVSNDGK PSDLPHTFEY VVGHTMERSP MHVRNVGNPS DLPRTFEFMK GHKHT 595 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |