CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025877
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA4149 protein 
Protein Synonyms/Alias
  
Gene Name
 Zhx1 
Gene Synonyms/Alias
 mKIAA4149 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
725PSAEEYDKLAEESGLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 DNA-binding; Homeobox; Nucleus. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 906 AA 
Protein Sequence
KPLFSNEGFQ TVLSLSAFKS PLRFPLIPAP KIKMASRRKS TTPCMVLASE QDPDLELISD 60
LDEGPPILTP VENAKAESVS SDEEVHGSVD SDNQQNKKVE GGYECKYCTF QTPDLNMFTF 120
HVDSEHPNVV LNSSYVCVEC NFLTKRYDAL SEHNLKYHPG EENFKLTMVK RNNQTIFEQT 180
INDLTFDGSF VKEENTEQGE SIDVSSSGIS ISKTPIMKMM KNKVENKRIT VHHNSAEGTS 240
EEKENGVKAS QEENAESVSS SALESNTSTS TINRVHPSPA STVVTPTAVL PGLAQVITAV 300
SAQQNSNLLP KVLIPVNSIP TYNAALDNNP LLLNTYNKFP YPTMSEITVL SAQAKYTEEQ 360
IKIWFSAQRL KHGVSWTPEE VEEARRKQFN GTVHTVPQTI TVIPTHISTG SNGLPSILQT 420
CQIVGQPGLV LTQVAGTNTL PVTAPIALTV AGVPNQTNVQ KSQVPAAQPA TDTKPATAAV 480
PSSPSVRPEA ALVNPDSFGI RAKKTKEQLA ELKVSYLKNQ FPHDSEIIRL MKITGLTKGE 540
IKKWFSDTRY NQRNSKSNQC LHLNNDSSAT IIIDSSDETP EPPAAAASQQ KQSWNPFPDF 600
APQKFKEKTA EQLRALQASF LNSSVLTDEE VNRLRAQTKL TRREIDAWFT EKNKTKALKD 660
EKIEVDESNV GSSKEEPGES SPGDETVAPK SGGTGKICKK TPEQLHMLKS AFVRTQWPSA 720
EEYDKLAEES GLARTDIVSW FGDTRYAWKN GNLKWYYYYQ SSNSSSLNGL SSLRRRGRGR 780
PKGRGRGRPR GRPRGGKRMN TWDRVPSLIK FKTGTAILKD YYLKHKFLNE QDLDELVNRS 840
HMGYEQVREW FAERQRRSEL GIELFEENEE EDEVVDDQEE DEEETDDSDT WEPPRHVKRK 900
LSKSDD 906 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara. 
Interpro
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 
Pfam
 PF00046; Homeobox 
SMART
 SM00389; HOX
 SM00355; ZnF_C2H2 
PROSITE
 PS50071; HOMEOBOX_2
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS