CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024543
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ethanolamine kinase 2 
Protein Synonyms/Alias
 EKI 2; Ethanolamine kinase-like protein 
Gene Name
 Etnk2 
Gene Synonyms/Alias
 Tuc1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
78RELRPHWKPEQVRTKubiquitination[1]
207HRYFTLVKDEISPSLubiquitination[1]
316RYYLEAQKGTAASPRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity. 
Sequence Annotation
  
Keyword
 Alternative splicing; ATP-binding; Complete proteome; Kinase; Lipid biosynthesis; Lipid metabolism; Nucleotide-binding; Phospholipid biosynthesis; Phospholipid metabolism; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 385 AA 
Protein Sequence
MAVPPSAPVP CSPFYLRRQE PCPQCSWSME EKAVASAGCW EPPGPPRAAV PCFSVTVEQD 60
DILPGALRLI RELRPHWKPE QVRTKRFKDG ITNKLLACYV EEDMRDCVLV RVYGERTELL 120
VDRENEVRNF QLLRAHGCAP KLYCTFQNGL CYEYVQGVAL GPEHIREPQL FRLIALEMAK 180
IHTIHANGSL PKPTLWHKMH RYFTLVKDEI SPSLSADVPK VEVLEQELAW LKEHLSQLDS 240
PVVFCHNDLL CKNIIYDSDK GRVCFIDYEY AGYNYQAFDI GNHFNEFAGV NVVDYSRYPA 300
RETQVQWLRY YLEAQKGTAA SPREVERLYA QVNKFALASH FFWALWALIQ NQYSTISFDF 360
LRYAVIRFNQ YFKVKPQVSA LEMPK 385 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004305; F:ethanolamine kinase activity; IDA:UniProtKB.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0035264; P:multicellular organism growth; IMP:MGI.
 GO:0006646; P:phosphatidylethanolamine biosynthetic process; IMP:MGI.
 GO:0001890; P:placenta development; IMP:MGI.
 GO:0009791; P:post-embryonic development; IMP:MGI. 
Interpro
 IPR026712; Cho/Etha_kinase.
 IPR011009; Kinase-like_dom. 
Pfam
  
SMART
  
PROSITE
  
PRINTS