CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016160
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serologically defined colon cancer antigen 8 
Protein Synonyms/Alias
 Antigen NY-CO-8; Centrosomal colon cancer autoantigen protein; hCCCAP 
Gene Name
 SDCCAG8 
Gene Synonyms/Alias
 CCCAP; NPHP10; HSPC085 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
229QLELEKLKLTYEEKCubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis. 
Sequence Annotation
 REGION 216 713 Sufficient for homodimerization (By
 REGION 533 713 Mediates interaction with OFD1.  
Keyword
 Alternative splicing; Cell junction; Ciliopathy; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Leber congenital amaurosis; Nephronophthisis; Polymorphism; Reference proteome; Senior-Loken syndrome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 713 AA 
Protein Sequence
MAKSPENSTL EEILGQYQRS LREHASRSIH QLTCALKEGD VTIGEDAPNL SFSTSVGNED 60
ARTAWPELQQ SHAVNQLKDL LRQQADKESE VSPSRRRKMS PLRSLEHEET NMPTMHDLVH 120
TINDQSQYIH HLEAEVKFCK EELSGMKNKI QVVVLENEGL QQQLKSQRQE ETLREQTLLD 180
ASGNMHNSWI TTGEDSGVGE TSKRPFSHDN ADFGKAASAG EQLELEKLKL TYEEKCEIEE 240
SQLKFLRNDL AEYQRTCEDL KEQLKHKEFL LAANTCNRVG GLCLKCAQHE AVLSQTHTNV 300
HMQTIERLVK ERDDLMSALV SVRSSLADTQ QREASAYEQV KQVLQISEEA NFEKTKALIQ 360
CDQLRKELER QAERLEKELA SQQEKRAIEK DMMKKEITKE REYMGSKMLI LSQNIAQLEA 420
QVEKVTKEKI SAINQLEEIQ SQLASREMDV TKVCGEMRYQ LNKTNMEKDE AEKEHREFRA 480
KTNRDLEIKD QEIEKLRIEL DESKQHLEQE QQKAALAREE CLRLTELLGE SEHQLHLTRQ 540
EKDSIQQSFS KEAKAQALQA QQREQELTQK IQQMEAQHDK TENEQYLLLT SQNTFLTKLK 600
EECCTLAKKL EQISQKTRSE IAQLSQEKRY TYDKLGKLQR RNEELEEQCV QHGRVHETMK 660
QRLRQLDKHS QATAQQLVQL LSKQNQLLLE RQSLSEEVDR LRTQLPSMPQ SDC 713 
Gene Ontology
 GO:0005911; C:cell-cell junction; IDA:UniProtKB.
 GO:0005814; C:centriole; IDA:UniProtKB.
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.
 GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
 GO:0035148; P:tube formation; ISS:UniProtKB. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS