UniProt Accession

 CXB1_RAT; P08033 

Genbank Protein ID

 X04070; X04303; M23565; BC078868; AH003192 

Genbank Nucleotide ID

 CAA27705.1; CAA27846.1; AAA81569.1; AAH78868.1; AAA75195.1 

Protein Name

 Gap junction beta-1 protein 

Protein Synonyms/Alias

 Connexin-32; Cx32; GAP junction 28 kDa liver protein 

Gene Name

 Gjb1 

Gene Synonyms/Alias

 Cxn-32 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
121	PLHLEEVKRHKVHIS	ubiquitination	[1, 2]
244	HRLSPEYKQNEINKL	ubiquitination	[1, 2]
250	YKQNEINKLLSEQDG	ubiquitination	[1, 2]
260	SEQDGSLKDILRRSP	ubiquitination	[1, 2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. 

Sequence Annotation

 MOD_RES 258 258 Phosphoserine (By similarity).
 MOD_RES 266 266 Phosphoserine.  

Keyword

 Cell junction; Cell membrane; Complete proteome; Direct protein sequencing; Gap junction; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 283 AA 

Protein Sequence

Gene Ontology

 GO:0005922; C:connexon complex; IEA:InterPro.
 GO:0005783; C:endoplasmic reticulum; IDA:RGD.
 GO:0005921; C:gap junction; IDA:RGD.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005243; F:gap junction channel activity; IDA:RGD.
 GO:0007154; P:cell communication; TAS:RGD.
 GO:0051259; P:protein oligomerization; IDA:RGD.
 GO:0015868; P:purine ribonucleotide transport; IDA:RGD. 

Interpro

 IPR000500; Connexin.
 IPR002267; Connexin32.
 IPR019570; Connexin_CCC.
 IPR017990; Connexin_CS.
 IPR013092; Connexin_N. 

Pfam

 PF00029; Connexin
 PF10582; Connexin_CCC 

SMART

 SM00037; CNX
 SM01089; Connexin_CCC 

PROSITE

 PS00407; CONNEXINS_1
 PS00408; CONNEXINS_2 

PRINTS

 PR00206; CONNEXIN.
 PR01138; CONNEXINB1.